Alireza Morovat
Overview
Explore the profile of Alireza Morovat including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
595
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Recent Articles
1.
Mogire R, Muriuki J, Morovat A, Mentzer A, Webb E, Kimita W, et al.
Nutrients
. 2022 Apr;
14(7).
PMID: 35405984
Vitamin D regulates the master iron hormone hepcidin, and iron in turn alters vitamin D metabolism. Although vitamin D and iron deficiency are highly prevalent globally, little is known about...
2.
Mogire R, Morovat A, Muriuki J, Mentzer A, Webb E, Kimita W, et al.
BMC Med
. 2021 May;
19(1):115.
PMID: 34011341
Background: Children living in sub-Saharan Africa have a high burden of rickets and infectious diseases, conditions that are linked to vitamin D deficiency. However, data on the vitamin D status...
3.
Muriuki J, Mentzer A, Mitchell R, Webb E, Etyang A, Kyobutungi C, et al.
Nat Med
. 2021 Feb;
27(4):653-658.
PMID: 33619371
Malaria and iron deficiency (ID) are common and interrelated public health problems in African children. Observational data suggest that interrupting malaria transmission reduces the prevalence of ID. To test the...
4.
Parmanand B, Watson M, Boland K, Ramamurthy N, Wharton V, Morovat A, et al.
JHEP Rep
. 2020 Sep;
2(6):100154.
PMID: 32995714
Background & Aims: Iron reduction by venesection has been the cornerstone of treatment for haemochromatosis for decades, and its reported health benefits are many. Repeated phlebotomy can lead to a...
5.
Muriuki J, Mentzer A, Webb E, Morovat A, Kimita W, Ndungu F, et al.
BMC Med
. 2020 Feb;
18(1):31.
PMID: 32102669
Background: Iron deficiency (ID) is a major public health burden in African children and accurate prevalence estimates are important for effective nutritional interventions. However, ID may be incorrectly estimated in...
6.
Morten K, Potter M, Badder L, Sivathondan P, Dragovic R, Neumann A, et al.
Wellcome Open Res
. 2019 Nov;
2:14.
PMID: 31754635
Mitochondrial diabetes is primarily caused by β-cell failure, a cell type whose unique properties are important in pathogenesis. By reducing glucose, we induced energetic stress in two rodent β-cell models...
7.
Lawton M, Baig F, Toulson G, Morovat A, Evetts S, Ben-Shlomo Y, et al.
Mov Disord
. 2019 Nov;
35(2):279-287.
PMID: 31693246
Background: Predicting prognosis in Parkinson's disease (PD) has important implications for individual prognostication and clinical trials design and targeting novel treatments. Blood biomarkers could help in this endeavor. Methods: We...
8.
Muriuki J, Mentzer A, Band G, Gilchrist J, Carstensen T, Lule S, et al.
Sci Adv
. 2019 Sep;
5(9):eaaw0109.
PMID: 31517041
Iron acquisition is critical for life. Ferroportin (FPN) exports iron from mature erythrocytes, and deletion of the gene results in hemolytic anemia and increased fatality in malaria-infected mice. The Q248H...
9.
Williams A, Ladva C, Leon J, Lopman B, Tangpricha V, Whitehead R, et al.
Am J Clin Nutr
. 2019 Sep;
110(6):1456-1464.
PMID: 31504095
Background: To accurately assess micronutrient status, it is necessary to characterize the effects of inflammation and the acute-phase response on nutrient biomarkers. Objective: Within a norovirus human challenge study, we...
10.
Lim P, Duarte T, Arezes J, Garcia-Santos D, Hamdi A, Pasricha S, et al.
Nat Metab
. 2019 Jul;
1(5):519-531.
PMID: 31276102
Iron is critical for life but toxic in excess because of iron-catalysed formation of pro-oxidants that cause tissue damage in a range of disorders. The Nrf2 transcription factor orchestrates cell-intrinsic...