Aline Barroso Spejo
Overview
Explore the profile of Aline Barroso Spejo including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
95
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0
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Recent Articles
1.
Perez M, Barroso Spejo A, Bortolanca Chiarotto G, Guimaraes F, de Oliveira A, Cartarozzi L
Neuroscience
. 2024 Oct;
565:265-276.
PMID: 39481830
Sciatic nerve crush in neonatal rats leads to an extensive death of motor and sensory neurons, serving as a platform to develop new neuroprotective approaches. The endocannabinoid system plays important...
2.
Sinopoulou E, Barroso Spejo A, Roopnarine N, Burnside E, Bartus K, de Winter F, et al.
J Neurosci Res
. 2022 Aug;
100(11):2055-2076.
PMID: 35916483
Cervical level spinal cord injury (SCI) can severely impact upper limb muscle function, which is typically assessed in the clinic using electromyography (EMG). Here, we established novel preclinical methodology for...
3.
Bortolanca Chiarotto G, Cartarozzi L, Perez M, Biscola N, Barroso Spejo A, Gubert F, et al.
J Neuroinflammation
. 2019 Nov;
16(1):218.
PMID: 31727149
Background: The development of new therapeutic strategies to treat amyotrophic lateral sclerosis (ALS) is of utmost importance. The use of cyclic nitroxides such as tempol may provide neuroprotection and improve...
4.
Barroso Spejo A, Teles C, Zuccoli G, de Oliveira A
J Neurosci Res
. 2018 Dec;
97(4):520-534.
PMID: 30549080
Astrogliosis and microglial reactions are correlated with the formation of scar tissue and synapse loss. 4-hydroxy-tempo (TEMPOL) is a reactive oxygen species scavenger with proven neuroprotective efficacy in experimental models...
5.
6.
Araujo M, Kyrylenko S, Barroso Spejo A, Castro M, Ferreira Junior R, Barraviera B, et al.
Exp Neurol
. 2017 Apr;
294:45-57.
PMID: 28450050
Ventral root avulsion (VRA) triggers a strong glial reaction which contributes to neuronal loss, as well as to synaptic detachment. To overcome the degenerative effects of VRA, treatments with neurotrophic...
7.
Biscola N, Cartarozzi L, Ulian-Benitez S, Barbizan R, Castro M, Barroso Spejo A, et al.
J Venom Anim Toxins Incl Trop Dis
. 2017 Mar;
23:13.
PMID: 28293254
Lesions to the nervous system often produce hemorrhage and tissue loss that are difficult, if not impossible, to repair. Therefore, scar formation, inflammation and cavitation take place, expanding the lesion...
8.
Barroso Spejo A, Oliveira A
Neuropharmacology
. 2014 Dec;
96(Pt A):113-23.
PMID: 25445484
Following axotomy, the contact between motoneurons and muscle fibers is disrupted, triggering a retrograde reaction at the neuron cell body within the spinal cord. Together with chromatolysis, a hallmark of...