Alina Theisen
Overview
Explore the profile of Alina Theisen including associated specialties, affiliations and a list of published articles.
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14
Citations
140
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Recent Articles
1.
Butalewicz J, Escobar E, Wootton C, Theisen A, Park M, Seeley E, et al.
Anal Chem
. 2024 Oct;
96(41):16154-16161.
PMID: 39365147
Ultraviolet photodissociation (UVPD) has been shown to be a versatile ion activation strategy for the characterization of peptides and intact proteins among other classes of biological molecules. Combining the high-performance...
2.
Wootton C, Maillard J, Theisen A, Brabeck G, Schat C, Ruger C, et al.
Anal Chem
. 2024 Jul;
96(28):11343-11352.
PMID: 38973712
Modern research faces increasingly complex materials with a constant need for new analytical strategies that can provide deeper levels of chemical insight. Ultrahigh resolution mass spectrometry (MS), particularly Fourier transform...
3.
Liu F, Ridgeway M, Wootton C, Theisen A, Panczyk E, Meier F, et al.
J Am Soc Mass Spectrom
. 2023 Aug;
34(10):2232-2246.
PMID: 37638640
"Top-down" proteomics analyzes intact proteins and identifies proteoforms by their intact mass as well as the observed fragmentation pattern in tandem mass spectrometry (MS/MS) experiments. Recently, hybrid ion mobility spectrometry-mass...
4.
Theisen A, Wootton C, Haris A, Morgan T, Lam Y, Barrow M, et al.
Anal Chem
. 2022 Nov;
94(45):15631-15638.
PMID: 36317856
Ultraviolet photodissociation is a fast, photon-mediated fragmentation method that yields high sequence coverage and informative cleavages of biomolecules. In this work, 193 nm UVPD was coupled with a 12 Tesla...
5.
Paris J, Theisen A, Marzullo B, Haris A, Morgan T, Barrow M, et al.
J Am Soc Mass Spectrom
. 2022 May;
33(7):1126-1133.
PMID: 35604791
Collisionally activated dissociation (CAD), infrared multiphoton dissociation (IRMPD), ultraviolet photodissociation (UVPD), electron capture dissociation and electron detachment dissociation (EDD) experiments were conducted on a set of phosphopeptides, in a Fourier...
6.
Haris A, Lam Y, Wootton C, Theisen A, Marzullo B, Schorr P, et al.
J Am Soc Mass Spectrom
. 2022 May;
33(6):1022-1030.
PMID: 35561028
Vitamin D compounds are a group of secosteroids derived from cholesterol that are vital for maintaining bone health in humans. Recent studies have shown extraskeletal effects of vitamin D, involving...
7.
Liu F, Ridgeway M, Winfred J, Polfer N, Lee J, Theisen A, et al.
Rapid Commun Mass Spectrom
. 2021 Sep;
35(22):e9192.
PMID: 34498312
Rationale: Tandem-ion mobility spectrometry/mass spectrometry methods have recently gained traction for the structural characterization of proteins and protein complexes. However, ion activation techniques currently coupled with tandem-ion mobility spectrometry/mass spectrometry...
8.
Marzullo B, Morgan T, Theisen A, Haris A, Wootton C, Perry S, et al.
Anal Chem
. 2021 Jul;
93(27):9462-9470.
PMID: 34192872
Ultraviolet photodissociation (UVPD) has been shown to produce extensive structurally informative data for a variety of chemically diverse compounds. Herein, we demonstrate the performance of the 193 nm UVPD fragmentation...
9.
Lermyte F, Theisen A, OConnor P
J Am Soc Mass Spectrom
. 2020 Nov;
32(1):364-372.
PMID: 33237779
One of the main characteristics of biomolecular ions in mass spectrometry is their net charge, and a range of approaches exist to either increase or decrease this quantity in the...
10.
Macpherson J, Theisen A, Masino L, Fets L, Driscoll P, Encheva V, et al.
Elife
. 2019 Jul;
8.
PMID: 31264961
Several enzymes can simultaneously interact with multiple intracellular metabolites, however, how the allosteric effects of distinct ligands are integrated to coordinately control enzymatic activity remains poorly understood. We addressed this...