Alicja Braczko
Overview
Explore the profile of Alicja Braczko including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
71
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Recent Articles
1.
Pyrczak-Felczykowska A, Kaczorowska A, Gieldon A, Braczko A, Smolenski R, Antosiewicz J, et al.
J Enzyme Inhib Med Chem
. 2025 Feb;
40(1):2465575.
PMID: 40013402
The impact of the isoxazole derivative of usnic acid, (formerly known as 2b) on cancer and non-cancerous cell metabolism was investigated. significantly reduced the utilisation of most metabolic substrates that...
2.
Braczko A, Stawarska K, Kawecka A, Walczak I, Slominska E, Kutryb-Zajac B, et al.
Nucleosides Nucleotides Nucleic Acids
. 2025 Feb;
:1-12.
PMID: 39895099
Mitochondrial dysfunction in failing hearts has been described as a driving force for energy deprivation and cardiomyocyte energy supply-demand imbalance. Isoproterenol (ISO), the β1/β2-adrenergic receptor agonist that leads to myocardial...
3.
Mierzejewska P, Denslow A, Papiernik D, Zabrocka A, Kutryb-Zajac B, Charkiewicz K, et al.
Int J Mol Sci
. 2025 Jan;
26(1.
PMID: 39795893
4-pyridone-3-carboxamide-1-β-D-ribonucleoside (4PYR) is a nicotinamide derivative, considered a new oncometabolite. 4PYR formation induced a cytotoxic effect on the endothelium. Elevated blood 4PYR concentration was observed in patients with cancer. Still,...
4.
Romanowska-Kocejko M, Braczko A, Jedrzejewska A, Zarczynska-Buchowiecka M, Kocejko T, Kutryb-Zajac B, et al.
Microvasc Res
. 2024 Sep;
157:104748.
PMID: 39293561
Long COVID is a complex pathophysiological condition. However, accumulating data suggests that COVID-19 is a systemic microvascular endothelial dysfunction with different clinical manifestations. In this study, a microvascular function was...
5.
Romanowska-Kocejko M, Jedrzejewska A, Braczko A, Stawarska K, Krol O, Franczak M, et al.
Biomedicines
. 2024 Mar;
12(3).
PMID: 38540167
Adenine nucleotides play a critical role in maintaining essential functions of red blood cells (RBCs), including energy metabolism, redox status, shape fluctuations and RBC-dependent endothelial and microvascular functions. Recently, it...
6.
Braczko A, Harasim G, Kawecka A, Walczak I, Kapusta M, Narajczyk M, et al.
Front Physiol
. 2023 Sep;
14:1216267.
PMID: 37745244
Statins and proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) are cornerstones of therapy to prevent cardiovascular disease, acting by lowering lipid concentrations and only partially identified pleiotropic effects. This study...
7.
Jedrzejewska A, Kawecka A, Braczko A, Romanowska-Kocejko M, Stawarska K, Deptula M, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37685949
Endothelial cells are a preferential target for SARS-CoV-2 infection. Previously, we have reported that vascular adenosine deaminase 1 (ADA1) may serve as a biomarker of endothelial activation and vascular inflammation,...
8.
Kutryb-Zajac B, Kawecka A, Nasadiuk K, Braczko A, Stawarska K, Caiazzo E, et al.
Biomed Pharmacother
. 2023 Jul;
165:115184.
PMID: 37506580
Adenosine is an endogenous nucleoside that regulates many physiological and pathological processes. It is derived from either the intracellular or extracellular dephosphorylation of adenosine triphosphate and interacts with cell-surface G-protein-coupled...
9.
Zabielska-Kaczorowska M, Braczko A, Pelikant-Malecka I, Slominska E, Smolenski R
Pharmaceuticals (Basel)
. 2023 Apr;
16(4).
PMID: 37111356
Myocardial ischemic adenosine production decreases in subsequent events that may blunt its protective functions. To test the relation between total or mitochondrial cardiac adenine nucleotide pool (TAN) on the energy...
10.
Braczko A, Kutryb-Zajac B, Jedrzejewska A, Krol O, Mierzejewska P, Zabielska-Kaczorowska M, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232794
Dyslipidemia triggers many severe pathologies, including atherosclerosis and chronic inflammation. Several lines of evidence, including our studies, have suggested direct effects of dyslipidemia on cardiac energy metabolism, but details of...