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Alfonso Mate

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Recent Articles
11.
Plastino F, Santana-Garrido A, Pesce N, Aronsson M, Lardner E, Mate A, et al.
Exp Eye Res . 2021 Feb; 206:108518. PMID: 33639134
Background: Echinomycin (EKN), an inhibitor of hypoxia-inducible factor (HIF)-1 DNA-binding activity, has been implied as a possible therapeutic agent in ischemic diseases. Here, we assess EKN in hypoxia-driven responses in...
12.
Salsoso R, Mate A, Toledo F, Vazquez C, Sobrevia L
Biochim Biophys Acta Mol Basis Dis . 2020 Oct; 1867(1):165993. PMID: 33096224
Late-onset preeclampsia (LOPE) associates with reduced umbilical vein reactivity and endothelial nitric oxide synthase (eNOS) activity but increased human cationic amino acid (hCAT-1)-mediated L-arginine transport involving A adenosine receptor in...
13.
Santana-Garrido A, Reyes-Goya C, Perez-Camino M, Andre H, Mate A, Vazquez C
Antioxidants (Basel) . 2020 Sep; 9(9). PMID: 32961933
Oxidative stress plays an important role in the pathogenesis of ocular diseases, including hypertensive eye diseases. The beneficial effects of olive oil on cardiovascular diseases might rely on minor constituents....
14.
Reyes-Goya C, Santana-Garrido A, Soto-Astacio E, Aramburu O, Zambrano S, Mate A, et al.
Toxics . 2020 Jul; 8(3). PMID: 32698382
Sunitinib (Su) is a tyrosine kinase inhibitor with antiangiogenic and antineoplastic effects that is recommended therapy for renal cell carcinoma, gastrointestinal stromal tumors, and pancreatic neuroendocrine tumors. Arterial hypertension is...
15.
Santana-Garrido A, Reyes-Goya C, Andre H, Aramburu O, Mate A, Vazquez C
Life Sci . 2020 Jul; 257:118072. PMID: 32659367
Aims: Sunitinib (Su), a tyrosine kinase inhibitor, is one of the most commonly used anti-angiogenic drugs. Some studies have described retinal detachment and photoreceptor damage following systemic exposure to Su,...
16.
Mate A, Blanca A, Salsoso R, Toledo F, Stiefel P, Sobrevia L, et al.
Curr Vasc Pharmacol . 2020 Jun; 18(4):423-424. PMID: 32519622
No abstract available.
17.
Mate A, Reyes-Goya C, Santana-Garrido A, Vazquez C
Curr Vasc Pharmacol . 2020 Apr; 19(2):132-140. PMID: 32234002
Healthy lifestyle habits spanning from preconception to postpartum are considered as a major safeguard for achieving successful pregnancies and for the prevention of gestational diseases. Among preconception priorities established by...
18.
Chiarello D, Abad C, Rojas D, Toledo F, Vazquez C, Mate A, et al.
Biochim Biophys Acta Mol Basis Dis . 2018 Dec; 1866(2):165354. PMID: 30590104
The role of oxidative stress in the physiopathology of human pregnancy is of particular interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a normal systemic inflammatory...
19.
Mate A, Blanca A, Salsoso R, Toledo F, Stiefel P, Sobrevia L, et al.
Curr Vasc Pharmacol . 2018 Nov; 17(5):455-464. PMID: 30426902
Pregnancy hypertensive disorders such as Preeclampsia (PE) are strongly correlated with insulin resistance, a condition in which the metabolic handling of D-glucose is deficient. In addition, the impact of preeclampsia...
20.
Chiarello D, Salsoso R, Toledo F, Mate A, Vazquez C, Sobrevia L
Mol Aspects Med . 2017 Dec; 60:69-80. PMID: 29222068
Intercellular communication is a critical process in biological mechanisms. During pregnancy foetoplacental tissues release a heterogeneous group of extracellular vesicles (EVs) that include exosomes, microvesicles, apoptotic bodies, and syncytial nuclear...