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» Authors » Sonia Zambrano

Sonia Zambrano

Explore the profile of Sonia Zambrano including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 289
Followers 0
Related Specialties
Nephrology
Science
Biochemistry
Top 10 Co-Authors
Alfonso Mate
Jaakko Patrakka
Carmen M Vazquez
Antonio J Blanca
Katja Moller-Hackbarth
Jose L Miguel-Carrasco
Emmanuelle Charrin
Maria V Ruiz-Armenta
Mark Lal
Annika Wernerson
Published In
Kidney Int
Sci Rep
J Inflamm (Lond)
Am J Hypertens
J Cell Biochem
Affiliations
Soon will be listed here.
Recent Articles
1.
Soluble Klotho protects against glomerular injury through regulation of ER stress response
Charrin E, Dabaghie D, Sen I, Unnersjo-Jess D, Moller-Hackbarth K, Burmakin M, et al.
Commun Biol . 2023 Feb; 6(1):208. PMID: 36813870
αKlotho (Klotho) has well established renoprotective effects; however, the molecular pathways mediating its glomerular protection remain incompletely understood. Recent studies have reported that Klotho is expressed in podocytes and protects...
2.
Molecular insights into the early stage of glomerular injury in IgA nephropathy using single-cell RNA sequencing
Zambrano S, He L, Kano T, Sun Y, Charrin E, Lal M, et al.
Kidney Int . 2021 Dec; 101(4):752-765. PMID: 34968552
IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide and defined by the presence of IgA-containing immune complexes in the mesangium that induce an inflammation leading to glomerulonephritis. Since...
3.
Retinoic acid receptor responder1 promotes development of glomerular diseases via the Nuclear Factor-κB signaling pathway
Moller-Hackbarth K, Dabaghie D, Charrin E, Zambrano S, Genove G, Li X, et al.
Kidney Int . 2021 Jun; 100(4):809-823. PMID: 34147551
Inflammatory pathways are activated in most glomerular diseases but molecular mechanisms driving them in kidney tissue are poorly known. We identified retinoic acid receptor responder 1 (Rarres1) as a highly...
4.
Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes
He B, Chen P, Zambrano S, Dabaghie D, Hu Y, Moller-Hackbarth K, et al.
Nat Commun . 2021 Apr; 12(1):2141. PMID: 33837218
Molecular characterization of the individual cell types in human kidney as well as model organisms are critical in defining organ function and understanding translational aspects of biomedical research. Previous studies...
5.
Novel insights into the disease transcriptome of human diabetic glomeruli and tubulointerstitium
Levin A, Reznichenko A, Witasp A, Liu P, Greasley P, Sorrentino A, et al.
Nephrol Dial Transplant . 2020 Aug; 35(12):2059-2072. PMID: 32853351
Background: Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, affecting ∼30% of the rapidly growing diabetic population, and strongly associated with cardiovascular risk. Despite this, the...
6.
Mechanism of Vascular Toxicity in Rats Subjected to Treatment with a Tyrosine Kinase Inhibitor
Reyes-Goya C, Santana-Garrido A, Soto-Astacio E, Aramburu O, Zambrano S, Mate A, et al.
Toxics . 2020 Jul; 8(3). PMID: 32698382
Sunitinib (Su) is a tyrosine kinase inhibitor with antiangiogenic and antineoplastic effects that is recommended therapy for renal cell carcinoma, gastrointestinal stromal tumors, and pancreatic neuroendocrine tumors. Arterial hypertension is...
7.
GPRC5b Modulates Inflammatory Response in Glomerular Diseases NF-B Pathway
Zambrano S, Moller-Hackbarth K, Li X, Rodriguez P, Charrin E, Schwarz A, et al.
J Am Soc Nephrol . 2019 Jul; 30(9):1573-1586. PMID: 31285284
Background: Inflammatory processes play an important role in the pathogenesis of glomerulopathies. Finding novel ways to suppress glomerular inflammation may offer a new way to stop disease progression. However, the...
8.
Coro2b, a podocyte protein downregulated in human diabetic nephropathy, is involved in the development of protamine sulphate-induced foot process effacement
Schwarz A, Moller-Hackbarth K, Ebarasi L, Unnersjo Jess D, Zambrano S, Blom H, et al.
Sci Rep . 2019 Jun; 9(1):8888. PMID: 31221975
Podocytes have an important role in the pathogenesis of diabetic nephropathy (DN). Podocyte foot process effacement, mediated largely by the actin-based cytoskeleton of foot processes, is commonly detected in DN...
9.
FYVE domain-containing protein ZFYVE28 regulates EGFR-signaling in podocytes but is not critical for the function of filtration barrier in mice
Zambrano S, Rodriguez P, Guo J, Moller-Hackbarth K, Schwarz A, Patrakka J
Sci Rep . 2018 Mar; 8(1):4712. PMID: 29549365
The kidney ultrafiltration barrier is formed of endothelial cells, the glomerular basement membrane and podocytes. Podocytes have a central role in normal physiology and disease pathogenesis of the glomerulus. Signaling...
10.
l-Carnitine ameliorates the oxidative stress response to angiotensin II by modulating NADPH oxidase through a reduction in protein kinase c activity and NF-κB translocation to the nucleus
Blanca A, Ruiz-Armenta M, Zambrano S, Miguel-Carrasco J, Gonzalez-Roncero F, Fortuno A, et al.
Food Chem . 2017 Mar; 228:356-366. PMID: 28317735
l-Carnitine (LC) exerts beneficial effects in arterial hypertension due, in part, to its antioxidant capacity. We investigated the signalling pathways involved in the effect of LC on angiotensin II (Ang...