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Alexis L Nolfi

Explore the profile of Alexis L Nolfi including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 102
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Recent Articles
1.
Kulkarni M, Popovic B, Nolfi A, Skillen C, Brown B
Biomaterials . 2025 Mar; 320:123204. PMID: 40056612
All implanted materials inevitably trigger an acute inflammatory response. The long-term outcome, however, is dependent on the trajectory of this response. This study investigates the effects of aging on the...
2.
Buckenmeyer M, Sukhwani M, Iftikhar A, Nolfi A, Xian Z, Dadi S, et al.
J Tissue Eng . 2023 Nov; 14:20417314231197282. PMID: 38029018
Female cancer patients who have undergone chemotherapy have an elevated risk of developing ovarian dysfunction and failure. Experimental approaches to treat iatrogenic infertility are evolving rapidly; however, challenges and risks...
3.
Behun M, Kulkarni M, Nolfi A, France C, Skillen C, Mahan M, et al.
Tissue Eng Part A . 2023 Nov; 30(1-2):84-93. PMID: 37917102
The ability to reinnervate a muscle in the absence of a viable nerve stump is a challenging clinical scenario. Direct muscle neurotization (DMN) is an approach to overcome this obstacle;...
4.
Hachim D, LoPresti S, Rege R, Umeda Y, Iftikhar A, Nolfi A, et al.
Biomater Sci . 2020 Sep; 8(20):5751-5762. PMID: 32945303
The host macrophage response to implants has shown to be affected by tissue location and physio-pathological conditions of the patient. Success in immunomodulatory strategies is thus predicated on the proper...
5.
Hachim D, Iftikhar A, LoPresti S, Nolfi A, Ravichandar S, Skillen C, et al.
J Control Release . 2019 May; 305:65-74. PMID: 31103676
The role of innate immunity and macrophages in the host response to biomaterials has received renewed attention. A context-dependent spectrum of macrophage phenotypes are shown to affect tissue integration and...
6.
Nolfi A, Brown B, Liang R, Palcsey S, Bonidie M, Abramowitch S, et al.
Am J Obstet Gynecol . 2016 Apr; 215(2):206.e1-8. PMID: 27094962
Background: Despite good anatomic and functional outcomes, urogynecologic polypropylene meshes that are used to treat pelvic organ prolapse and stress urinary incontinence are associated with significant complications, most commonly mesh...
7.
Brown B, Mani D, Nolfi A, Liang R, Abramowitch S, Moalli P
Am J Obstet Gynecol . 2015 Aug; 213(5):668.e1-10. PMID: 26259906
Objective: We sought to determine the predominant cell type (macrophage, T lymphocyte, B lymphocyte, mast cell) within the area of implantation of the prototypical polypropylene mesh, Gynemesh PS (Ethicon, Somerville,...