Alexey V Shevelkin
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Explore the profile of Alexey V Shevelkin including associated specialties, affiliations and a list of published articles.
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11
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121
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Recent Articles
1.
Ratovitski T, Holland C, OMeally R, Shevelkin A, Shi T, Cole R, et al.
bioRxiv
. 2025 Jan;
PMID: 39763784
Huntington's Disease (HD), a progressive neurodegenerative disorder with no disease-modifying therapies, is caused by a CAG repeat expansion in the HD gene encoding polyglutamine-expanded huntingtin (HTT) protein. Mechanisms of HD...
2.
Ratovitski T, Jiang M, OMeally R, Rauniyar P, Chighladze E, Farago A, et al.
Hum Mol Genet
. 2021 Dec;
31(10):1651-1672.
PMID: 34888656
Huntington's disease (HD) is an incurable neurodegenerative disorder caused by a CAG expansion in the huntingtin gene (HTT). Post-translational modifications of huntingtin protein (HTT), such as phosphorylation, acetylation and ubiquitination,...
3.
Vaccari Cardoso B, Shevelkin A, Terrillion C, Mychko O, Mosienko V, Kasparov S, et al.
Glia
. 2021 Jan;
69(5):1241-1250.
PMID: 33400321
Astrocytes are in control of metabolic homeostasis in the brain and support and modulate neuronal function in various ways. Astrocyte-derived l-lactate (lactate) is thought to play a dual role as...
4.
Shevelkin A, Terrillion C, Hasegawa Y, Mychko O, Jouroukhin Y, Sawa A, et al.
Hum Mol Genet
. 2020 Aug;
29(17):2936-2950.
PMID: 32803234
Our understanding of the contribution of genetic risk factors to neuropsychiatric diseases is limited to abnormal neurodevelopment and neuronal dysfunction. Much less is known about the mechanisms whereby risk variants...
5.
Jouroukhin Y, Zhu X, Shevelkin A, Hasegawa Y, Abazyan B, Saito A, et al.
Biol Psychiatry
. 2018 Sep;
85(11):891-903.
PMID: 30219209
Background: Although several studies have linked adolescent cannabis use to long-term cognitive dysfunction, there are negative reports as well. The fact that not all users develop cognitive impairment suggests a...
6.
Shevelkin A, Terrillion C, Abazyan B, Kajstura T, Jouroukhin Y, Rudow G, et al.
Neurobiol Dis
. 2017 Aug;
108:362.
PMID: 28800926
No abstract available.
7.
Terrillion C, Abazyan B, Yang Z, Crawford J, Shevelkin A, Jouroukhin Y, et al.
Neuropsychopharmacology
. 2017 Jun;
42(11):2242-2251.
PMID: 28631721
The functional role of genetic variants in glia in the pathogenesis of psychiatric disorders remains poorly studied. Disrupted-In-Schizophrenia 1 (DISC1), a genetic risk factor implicated in major mental disorders, has...
8.
Shevelkin A, Terrillion C, Abazyan B, Kajstura T, Jouroukhin Y, Rudow G, et al.
Neurobiol Dis
. 2017 Apr;
103:144-153.
PMID: 28392471
In addition to motor function, the cerebellum has been implicated in cognitive and social behaviors. Various structural and functional abnormalities of Purkinje cells (PCs) have been observed in schizophrenia and...
9.
Nikitin V, Solntseva S, Kozyrev S, Nikitin P, Shevelkin A
Brain Res
. 2016 Mar;
1642:104-113.
PMID: 27017957
Memory reconsolidation processes and protein kinase Mzeta (PKMzeta) activity in memory maintenance and reorganization are poorly understood. Therefore, we examined memory reconsolidation and PKMzeta activity during the maintenance and reorganization...
10.
Nikitin V, Solntseva S, Shevelkin A
Learn Behav
. 2016 Jan;
44(3):250-9.
PMID: 26742927
Recent studies report that long-term memory retrieval can induce memory reconsolidation, and impairment of this reconsolidation might lead to amnesia. Previously, we found that reconsolidation of a conditioned food aversion...