Alexei S Soares
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Explore the profile of Alexei S Soares including associated specialties, affiliations and a list of published articles.
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52
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829
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Recent Articles
1.
Bernstein H, Soares A, Horvat K, Jakoncic J
J Synchrotron Radiat
. 2025 Feb;
32(Pt 2):385-398.
PMID: 39913307
New higher-count-rate, integrating, large-area X-ray detectors with framing rates as high as 17400 images per second are beginning to be available. These will soon be used for specialized macromolecular crystallography...
2.
Bernstein H, Soares A, Horvat K, Jakoncic J
bioRxiv
. 2024 Sep;
PMID: 39314279
Synopsis: New higher-count-rate, integrating, large area X-ray detectors with framing rates as high as 17,400 images per second are beginning to be available. These will soon be used for specialized...
3.
Klontz E, Obi J, Wang Y, Glendening G, Carr J, Tsibouris C, et al.
J Biol Chem
. 2023 Sep;
299(11):105290.
PMID: 37758001
Toll-like and interleukin-1/18 receptor/resistance (TIR) domain-containing proteins function as important signaling and immune regulatory molecules. TIR domain-containing proteins identified in eukaryotic and prokaryotic species also exhibit NAD+ hydrolase activity in...
4.
Schneider D, Soares A, Lazo E, Kreitler D, Qian K, Fuchs M, et al.
J Synchrotron Radiat
. 2022 Nov;
29(Pt 6):1480-1494.
PMID: 36345756
The highly automated macromolecular crystallography beamline AMX/17-ID-1 is an undulator-based high-intensity (>5 × 10 photons s), micro-focus (7 µm × 5 µm), low-divergence (1 mrad × 0.35 mrad) energy-tunable (5-18 ...
5.
Andi B, Kumaran D, Kreitler D, Soares A, Keereetaweep J, Jakoncic J, et al.
Sci Rep
. 2022 Jul;
12(1):12197.
PMID: 35842458
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), threatens global public health. The world needs rapid development of new antivirals and vaccines to control the current...
6.
Soares A, Yamada Y, Jakoncic J, McSweeney S, Sweet R, Skinner J, et al.
Acta Crystallogr F Struct Biol Commun
. 2022 Jul;
78(Pt 7):281-288.
PMID: 35787556
KAMO and BLEND provide particularly effective tools to automatically manage the merging of large numbers of data sets from serial crystallography. The requirement for manual intervention in the process can...
7.
Nguyen T, Phan K, Kozakov D, Gabelli S, Kreitler D, Andrews L, et al.
Acta Crystallogr D Struct Biol
. 2022 Mar;
78(Pt 3):268-277.
PMID: 35234141
One often observes small but measurable differences in the diffraction data measured from different crystals of a single protein. These differences might reflect structural differences in the protein and may...
8.
Schuller M, Correy G, Gahbauer S, Fearon D, Wu T, Diaz R, et al.
Sci Adv
. 2021 Apr;
7(16).
PMID: 33853786
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain within the nonstructural protein 3 counteracts host-mediated antiviral adenosine diphosphate-ribosylation signaling. This enzyme is a promising antiviral target because catalytic mutations...
9.
Olmeda I, Casino P, Collins R, Sendra R, Callejon S, Huesa J, et al.
Microb Biotechnol
. 2021 Feb;
14(3):1026-1043.
PMID: 33635570
Prokaryotic laccases are emergent biocatalysts. However, they have not been broadly found and characterized in bacterial organisms, especially in lactic acid bacteria. Recently, a prokaryotic laccase from the lactic acid...
10.
Schuller M, Correy G, Gahbauer S, Fearon D, Wu T, Diaz R, et al.
bioRxiv
. 2020 Dec;
PMID: 33269349
The SARS-CoV-2 macrodomain (Mac1) within the non-structural protein 3 (Nsp3) counteracts host-mediated antiviral ADP-ribosylation signalling. This enzyme is a promising antiviral target because catalytic mutations render viruses non-pathogenic. Here, we...