Alexei G Basnakian
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Explore the profile of Alexei G Basnakian including associated specialties, affiliations and a list of published articles.
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61
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1050
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Recent Articles
1.
Tesfay M, Zhang Y, Ferdous K, Taylor M, Cios A, Shelton R, et al.
Mol Ther Oncol
. 2025 Jan;
32(4):200913.
PMID: 39758249
Members of the genus including Jurona virus (JURV) have emerged as promising immunotherapeutic agents, characterized by their tumor selectivity, fast kinetics, low seroprevalence, and minimal toxicity in humans. Here, we...
2.
Adhikary S, Roy S, Budhathoki S, Chowdhury S, Stillwell A, Basnakian A, et al.
RSC Med Chem
. 2024 Dec;
PMID: 39703801
Melanoma, the most fatal form of skin cancer, often becomes resistant to the current therapeutic approaches in most patients. To explore new treatment options, fused thiazole derivatives were synthesized, and...
3.
Wang X, Sato A, Marino S, Akel N, Boysen G, Basnakian A, et al.
J Med Chem
. 2024 Nov;
67(22):20708-20720.
PMID: 39540576
Glucocorticoid-induced osteoporosis (GIOP) is the leading cause of iatrogenic osteoporosis due to the widespread clinical use of glucocorticoids (GC) as immunosuppressants. Previous research identified the proline-rich tyrosine kinase 2, Pyk2,...
4.
Ferdous K, Tesfay M, Cios A, Shelton R, Hartupee C, Urbaniak A, et al.
Biomedicines
. 2024 Jul;
12(7).
PMID: 39062169
About one-fourth of patients with pancreatic ductal adenocarcinoma (PDAC) are categorized as borderline resectable (BR) or locally advanced (LA). Chemotherapy and radiation therapy have not yielded the anticipated outcomes in...
5.
Garg S, Garg T, Miousse I, Wise S, Fatanmi O, Savenka A, et al.
Antioxidants (Basel)
. 2022 Oct;
11(10).
PMID: 36290618
Exposure to high doses of radiation, accidental or therapeutic, often results in gastrointestinal (GI) injury. To date, there are no therapies available to mitigate GI injury after radiation exposure. Gamma-tocotrienol...
6.
Rezaei Cherati S, Anas M, Liu S, Shanmugam S, Pandey K, Angtuaco S, et al.
ACS Nano
. 2022 Jul;
16(8):12061-12072.
PMID: 35868016
Carbon-based nanomaterials (CBNs) are often used for potential agricultural applications. Since CBNs applied to plants can easily enter plant organs and reach the human diet, the consequences of the introduction...
7.
Garg S, Garg T, Wise S, Fatanmi O, Miousse I, Savenka A, et al.
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35563033
The gastrointestinal (GI) system is highly susceptible to irradiation. Currently, there is no Food and Drug Administration (FDA)-approved medical countermeasures for GI radiation injury. The vitamin E analog gamma-tocotrienol (GT3)...
8.
Chambers S, Newman M, Frangie M, Savenka A, Basnakian A, Alam M
R Soc Open Sci
. 2021 Aug;
8(8):210395.
PMID: 34430045
The discovery of chimeric anti-melanoma agents is reported. These molecules are potent growth suppressors of melanoma cells with growth inhibition of 50% (GI) values as low as 1.32 µM. Compounds...
9.
Basnakian A, Moore C
J Cell Mol Med
. 2021 Jun;
25(14):6496-6499.
PMID: 34085765
DNA fragmentation produced by apoptotic DNases (endonucleases) leads to irreversible cell death. Although apoptotic DNases are simultaneously induced following toxic/oxidative cell injury and/or failed DNA repair, the study of DNases...
10.
Wang W, Li J, Tan J, Wang M, Yang J, Zhang Z, et al.
Nat Commun
. 2021 Jan;
12(1):476.
PMID: 33473107
Endonuclease G (ENDOG), a mitochondrial nuclease, is known to participate in many cellular processes, including apoptosis and paternal mitochondrial elimination, while its role in autophagy remains unclear. Here, we report...