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Alexandre Maciel-Guerra

Explore the profile of Alexandre Maciel-Guerra including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Maciel-Guerra A, Babaarslan K, Baker M, Rahman A, Hossain M, Sadique A, et al.
Nat Commun . 2024 Sep; 15(1):8231. PMID: 39313510
In Bangladesh, Vibrio cholerae lineages are undergoing genomic evolution, with increased virulence and spreading ability. However, our understanding of the genomic determinants influencing lineage transmission and disease severity remains incomplete....
2.
Baker M, Zhang X, Maciel-Guerra A, Babaarslan K, Dong Y, Wang W, et al.
Nat Commun . 2024 Jan; 15(1):206. PMID: 38182559
Sharing of genetic elements among different pathogens and commensals inhabiting same hosts and environments has significant implications for antimicrobial resistance (AMR), especially in settings with high antimicrobial exposure. We analysed...
3.
Baker M, Zhang X, Maciel-Guerra A, Dong Y, Wang W, Hu Y, et al.
Nat Food . 2023 Aug; 4(8):707-720. PMID: 37563495
China is the largest global consumer of antimicrobials and improving surveillance methods could help to reduce antimicrobial resistance (AMR) spread. Here we report the surveillance of ten large-scale chicken farms...
4.
Talhouni S, Fadhil W, Mongan N, Field L, Hunter K, Makhsous S, et al.
Front Immunol . 2023 May; 14:1057292. PMID: 37251410
Introduction: Characterization of the tumour immune infiltrate (notably CD8+ T-cells) has strong predictive survival value for cancer patients. Quantification of CD8 T-cells alone cannot determine antigenic experience, as not all...
5.
Maciel-Guerra A, Baker M, Hu Y, Wang W, Zhang X, Rong J, et al.
ISME J . 2022 Sep; 17(1):21-35. PMID: 36151458
A debate is currently ongoing as to whether intensive livestock farms may constitute reservoirs of clinically relevant antimicrobial resistance (AMR), thus posing a threat to surrounding communities. Here, combining shotgun...
6.
Peng Z, Maciel-Guerra A, Baker M, Zhang X, Hu Y, Wang W, et al.
PLoS Comput Biol . 2022 Mar; 18(3):e1010018. PMID: 35333870
Anthropogenic environments such as those created by intensive farming of livestock, have been proposed to provide ideal selection pressure for the emergence of antimicrobial-resistant Escherichia coli bacteria and antimicrobial resistance...
7.
Pearcy N, Hu Y, Baker M, Maciel-Guerra A, Xue N, Wang W, et al.
mSystems . 2021 Aug; 6(4):e0091320. PMID: 34342537
Antimicrobial resistance (AMR) is becoming one of the largest threats to public health worldwide, with the opportunistic pathogen Escherichia coli playing a major role in the AMR global health crisis....
8.
Esener N, Maciel-Guerra A, Giebel K, Lea D, Green M, Bradley A, et al.
PLoS Comput Biol . 2021 Jun; 17(6):e1009108. PMID: 34115749
Staphylococcus aureus is a serious human and animal pathogen threat exhibiting extraordinary capacity for acquiring new antibiotic resistance traits in the pathogen population worldwide. The development of fast, affordable and...
9.
Wang W, Baker M, Hu Y, Xu J, Yang D, Maciel-Guerra A, et al.
mSystems . 2021 Jun; 6(3):e0118520. PMID: 34100643
Staphylococcus aureus is a worldwide leading cause of numerous diseases ranging from food-poisoning to lethal infections. Methicillin-resistant S. aureus (MRSA) has been found capable of acquiring resistance to most antimicrobials....
10.
Maciel-Guerra A, Esener N, Giebel K, Lea D, Green M, Bradley A, et al.
Sci Rep . 2021 Apr; 11(1):7736. PMID: 33833319
Streptococcus uberis is one of the leading pathogens causing mastitis worldwide. Identification of S. uberis strains that fail to respond to treatment with antibiotics is essential for better decision making...