Alexandre E Nowill
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Explore the profile of Alexandre E Nowill including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
336
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0
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Recent Articles
1.
Nowill A, Caruso M, de Campos-Lima P
Front Immunol
. 2023 Jun;
14:1133225.
PMID: 37388738
Humanity did surprisingly well so far, considering how unprepared it was to respond to the coronavirus disease 2019 (COVID-19) threat. By blending old and ingenious new technology in the context...
2.
Nowill A, de Campos-Lima P
J Immunol
. 2020 Sep;
205(10):2566-2575.
PMID: 32958687
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which rapidly became a pandemic of global proportions. Sepsis is commonly present with high lethality in the severe...
3.
Seidinger A, Caminha I, Mastellaro M, Gabetta C, Nowill A, Pinheiro V, et al.
Mol Genet Genomic Med
. 2020 Jun;
8(9):e1168.
PMID: 32592449
Background: The p.Arg337His mutation of the TP53 is the most frequent germline missense variant associated with cancer described so far in this gene. It is mainly found in the South...
4.
Nowill A, Fornazin M, Spago M, Dorgan Neto V, Pinheiro V, Alexandre S, et al.
J Immunol
. 2019 Jul;
203(5):1298-1312.
PMID: 31358659
Cure of severe infections, sepsis, and septic shock with antimicrobial drugs is a challenge because morbidity and mortality in these conditions are essentially caused by improper immune response. We have...
5.
Fratoni E, Claudino V, Yunes R, Franchi Jr G, Nowill A, Filho V, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2016 Apr;
389(7):791-7.
PMID: 27095358
Drimys brasiliensis Miers (Winteraceae) is used in folk medicine for the treatment of cancer. Its anti-tumor activity has been demonstrated in vitro models using extracts and isolated compounds. This study...
6.
de Vasconcellos J, Laranjeira A, Leal P, Bhasin M, Zenatti P, Nunes R, et al.
PLoS One
. 2015 Aug;
10(8):e0134783.
PMID: 26302043
Acute Lymphoblastic Leukemia (ALL) is the most frequent childhood malignancy. In the effort to find new anti-leukemic agents, we evaluated the small drug SB225002 (N-(2-hydroxy-4-nitrophenyl)-N'-(2-bromophenyl)urea). Although initially described as a...
7.
Damiao M, Pasqualoto K, Ferreira A, Teixeira S, Azevedo R, Barbuto J, et al.
Arch Pharm (Weinheim)
. 2014 Oct;
347(12):885-95.
PMID: 25283529
A novel class of benzo[d][1,3]dioxol-5-ylmethyl alkyl/aryl amide and ester analogues of capsaicin were designed, synthesized, and evaluated for their cytotoxic activity against human and murine cancer cell lines (B16F10, SK-MEL-28,...
8.
Ferreira E, Reigada J, Correia M, Young M, Guimaraes E, Franchi Jr G, et al.
J Nat Prod
. 2014 Jun;
77(6):1377-82.
PMID: 24905499
Bioactivity-guided fractionation of the separate CH2Cl2 extracts from the aerial parts of Peperomia alata and P. trineura yielded seven polyketides: alatanone A [3-hydroxy-2-(5'-phenylpent-4'E-enoyl)cyclohex-2-en-1-one, 1a] and alatanone B [3-hydroxy-2-(3'-phenyl-6'-methylenedioxypropanoyl)cyclohex-2-en-1-one, 2a] from...
9.
Freitas G, Batista Jr J, Franchi Jr G, Nowill A, Yamaguchi L, Vilcachagua J, et al.
Phytochemistry
. 2013 Nov;
97:81-7.
PMID: 24252268
The EtOAc extract from the leaves of Piper carniconnectivum C. DC. was subjected to chromatographic separation to afford two non-aromatic B-ring flavanone compounds: 5-hydroxy-2-(1'-hydroxy-4'-oxo-cyclohex-2'-en-1'-yl)-6,7-dimethoxy-2,3-dihydro-4H-chromen-4-one (1) and 5-hydroxy-2-(1',2'-dihydroxy-4'-oxo-cyclohexyl)-6,7-dimethoxy-2,3-dihydro-4H-chromen-4-one (2). The absolute...
10.
Klein J, Nowill A, Franchi Jr G, Biavatti M, Quintao N, de Freitas R
Basic Clin Pharmacol Toxicol
. 2013 Jun;
113(5):307-15.
PMID: 23763911
Vernonia scorpioides (Lam.) Pers., popularly known as Enxuga, Erva-de-São Simão and Piracá, has been used in folk medicine for its anti-inflammatory, wound healing and antimicrobial properties. Two polyacetylenes, 5-octa-2,4,6-triynyl-furan-2(5H)-one (1)...