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Alexandre Destere

Explore the profile of Alexandre Destere including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 103
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Recent Articles
1.
Gerard A, Merino D, Benzaquen J, Destere A, Borchiellini D, Gosset C, et al.
Front Immunol . 2025 Feb; 16:1514033. PMID: 39911399
Background: Transplant recipients face increased cancer mortality due to immunosuppressive treatments. Immune checkpoint inhibitors (ICI) have improved survival rates, but data on the use of these agents in transplant recipients...
2.
Destere A, Gerard A, Merino D, Ewig E, Rocher F, Ben Othmann N, et al.
Therapie . 2024 Dec; PMID: 39694791
No abstract available.
3.
Woillard J, Benoist C, Destere A, Labriffe M, Marchello G, Josse J, et al.
CPT Pharmacometrics Syst Pharmacol . 2024 Oct; 14(1):82-94. PMID: 39412034
The use of synthetic data in pharmacology research has gained significant attention due to its potential to address privacy concerns and promote open science. In this study, we implemented and...
4.
Hemar V, Bouchet S, Ribeiro E, Prier P, Elleau C, Solas C, et al.
J Antimicrob Chemother . 2024 Sep; 79(12):3354-3355. PMID: 39347710
No abstract available.
5.
Rivals F, Goutelle S, Codde C, Garreau R, Ponthier L, Marquet P, et al.
Clin Pharmacokinet . 2024 Jul; 63(8):1137-1146. PMID: 39085523
Background And Objective: The dosage of daptomycin is usually based on body weight. However, it has been shown that this approach yields too high an exposure in obese patients. Pharmacokinetic...
6.
Rubera I, Clotaire L, Laurain A, Destere A, Martin L, Duranton C, et al.
Int J Mol Sci . 2024 Jun; 25(12). PMID: 38928212
Pseudoxanthoma elasticum (PXE) is a rare inherited systemic disease responsible for a juvenile peripheral arterial calcification disease. The clinical diagnosis of PXE is only based on a complex multi-organ phenotypic...
7.
Codde C, Rivals F, Destere A, Fromage Y, Labriffe M, Marquet P, et al.
Antimicrob Agents Chemother . 2024 Mar; 68(5):e0141523. PMID: 38501807
Daptomycin is a concentration-dependent lipopeptide antibiotic for which exposure/effect relationships have been shown. Machine learning (ML) algorithms, developed to predict the individual exposure to drugs, have shown very good performances...
8.
Ponthier L, Autmizguine J, Franck B, Asberg A, Ovetchkine P, Destere A, et al.
Clin Pharmacokinet . 2024 Mar; 63(4):539-550. PMID: 38492206
Background And Objectives: Ganciclovir (GCV) and valganciclovir (VGCV) show large interindividual pharmacokinetic variability, particularly in children. The objectives of this study were (1) to develop machine learning (ML) algorithms trained...
9.
Merino D, Gerard A, Destere A, Saidessalam H, Askenazy F, Montastruc F, et al.
Psychiatry Res . 2024 Feb; 334:115786. PMID: 38387164
A significant heterogeneity prevails in antipsychotics (APs) safety monitoring recommendations. Youths are deemed more vulnerable to cardiometabolic side effects. We aimed to assess age-dependent reporting of cardiac and metabolic disorders...
10.
Destere A, Marchello G, Merino D, Ben Othman N, Gerard A, Lavrut T, et al.
Br J Clin Pharmacol . 2024 Feb; 90(5):1258-1267. PMID: 38332645
Aims: Monitoring drug safety in real-world settings is the primary aim of pharmacovigilance. Frequent adverse drug reactions (ADRs) are usually identified during drug development. Rare ones are mostly characterized through...