Alexandre Coudray
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Explore the profile of Alexandre Coudray including associated specialties, affiliations and a list of published articles.
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10
Citations
357
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Recent Articles
1.
Pulver C, Grun D, Duc J, Sheppard S, Planet E, Coudray A, et al.
Genome Biol
. 2023 Nov;
24(1):258.
PMID: 37950299
Background: Transposable elements (TEs) have colonized the genomes of most metazoans, and many TE-embedded sequences function as cis-regulatory elements (CREs) for genes involved in a wide range of biological processes...
2.
de Tribolet-Hardy J, Thorball C, Forey R, Planet E, Duc J, Coudray A, et al.
Genome Res
. 2023 Sep;
33(8):1409-1423.
PMID: 37730438
Krüppel-associated box (KRAB) domain-containing zinc finger proteins (KZFPs) are one of the largest groups of transcription factors encoded by tetrapods, with 378 members in human alone. KZFP genes are often...
3.
Simo-Riudalbas L, Offner S, Planet E, Duc J, Abrami L, Dind S, et al.
Nat Commun
. 2022 Aug;
13(1):4913.
PMID: 35987910
The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor...
4.
Iouranova A, Grun D, Rossy T, Duc J, Coudray A, Imbeault M, et al.
Mob DNA
. 2022 Jan;
13(1):4.
PMID: 35042549
Background: Transposable element-embedded regulatory sequences (TEeRS) and their KRAB-containing zinc finger protein (KZFP) controllers are increasingly recognized as modulators of gene expression. We aim to characterize the contribution of this...
5.
Playfoot C, Duc J, Sheppard S, Dind S, Coudray A, Planet E, et al.
Genome Res
. 2021 Aug;
31(9):1531-1545.
PMID: 34400477
Transposable elements (TEs) account for more than 50% of the human genome and many have been co-opted throughout evolution to provide regulatory functions for gene expression networks. Several lines of...
6.
Ito J, Kimura I, Soper A, Coudray A, Koyanagi Y, Nakaoka H, et al.
Sci Adv
. 2020 Oct;
6(43).
PMID: 33087347
Gene expression aberration is a hallmark of cancers, but the mechanisms underlying such aberrations remain unclear. Human endogenous retroviruses (HERVs) are genomic repetitive elements that potentially function as enhancers. Since...
7.
Turelli P, Playfoot C, Grun D, Raclot C, Pontis J, Coudray A, et al.
Sci Adv
. 2020 Sep;
6(35):eaba3200.
PMID: 32923624
In the first days of embryogenesis, transposable element-embedded regulatory sequences (TEeRS) are silenced by Kruppel-associated box (KRAB) zinc finger proteins (KZFPs). Many TEeRS are subsequently co-opted in transcription networks, but...
8.
Pontis J, Planet E, Offner S, Turelli P, Duc J, Coudray A, et al.
Cell Stem Cell
. 2019 Apr;
24(5):724-735.e5.
PMID: 31006620
Expansion of transposable elements (TEs) coincides with evolutionary shifts in gene expression. TEs frequently harbor binding sites for transcriptional regulators, thus enabling coordinated genome-wide activation of species- and context-specific gene...
9.
de Iaco A, Coudray A, Duc J, Trono D
EMBO Rep
. 2019 Apr;
20(5).
PMID: 30948459
After fertilization of the transcriptionally silent oocyte, expression from both parental chromosomes is launched through zygotic genome activation (ZGA), occurring in the mouse at the 2-cell (2C) stage. Among the...
10.
Coudray A, Battenhouse A, Bucher P, Iyer V
PeerJ
. 2018 Aug;
6:e5362.
PMID: 30083469
To detect functional somatic mutations in tumor samples, whole-exome sequencing (WES) is often used for its reliability and relative low cost. RNA-seq, while generally used to measure gene expression, can...