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Alexandra Svensson

Explore the profile of Alexandra Svensson including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 185
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Recent Articles
1.
Reyahi A, Studahl M, Skouboe M, Fruhwurth S, Narita R, Ren F, et al.
JCI Insight . 2023 Nov; 8(21. PMID: 37937644
The mechanisms underlying susceptibility to recurrent herpes simplex virus type 2 (HSV-2) meningitis remain incompletely understood. In a patient experiencing multiple episodes of HSV-2 meningitis, we identified a monoallelic variant...
2.
Lind L, Svensson A, Thorn K, Krzyzowska M, Eriksson K
J Neurovirol . 2021 Jan; 27(1):145-153. PMID: 33492607
Herpes simplex virus type 2 (HSV-2) is a neurotropic virus that can cause meningitis, an inflammation of the meninges in the central nervous system. T cells are key players in...
3.
Eriksson K, Svensson A, Hait A, Schluter K, Tunback P, Nordstrom I, et al.
J Immunol . 2017 Sep; 199(8):2613-2617. PMID: 28893956
IFN-γ-inducible protein 16 (IFI16) is an immunological DNA sensor proposed to act in the cyclic GMP-AMP synthase-stimulator of IFN genes pathway. Because mice do not have a clear ortholog of...
4.
Svensson A, Patzi Churqui M, Schluter K, Lind L, Eriksson K
PLoS One . 2017 Aug; 12(8):e0183268. PMID: 28809949
Intracellular DNA- and RNA-sensing receptors, such as the IFN-inducible protein Absent in Melanoma 2 (AIM2), serve as host sensors against a wide range of infections. Immune sensing and inflammasome activation...
5.
Patzi Churqui M, Lind L, Thorn K, Svensson A, Savolainen O, Aranda K, et al.
J Ethnopharmacol . 2017 Aug; 210:192-197. PMID: 28807852
Ethnopharmacological Relevance: Equisetum giganteum L and Copaifera reticulate Ducke have been traditionally used by women of the Tacana tribe in the Bolivian Amazonas for genital hygiene and for treatment of...
6.
Svensson A, Tunback P, Nordstrom I, Shestakov A, Padyukov L, Eriksson K
J Virol . 2012 Jun; 86(17):9409-15. PMID: 22718836
STAT4 is an important transcription factor that contributes to the incidence and severity of different autoimmune diseases and is implicated in the antiviral immune responses in mice. In this study,...
7.
Svensson A, Tunback P, Nordstrom I, Padyukov L, Eriksson K
J Gen Virol . 2012 May; 93(Pt 8):1717-1724. PMID: 22552940
Lack of Toll-like receptor 3 (TLR3) functional activity predisposes children to human herpesvirus 1 (HSV-1) encephalitis. In this study, we have investigated whether there is any link between TLR3 and...
8.
Bjorkstrom N, Svensson A, Malmberg K, Eriksson K, Ljunggren H
PLoS One . 2011 Nov; 6(11):e27664. PMID: 22110712
Human natural killer (NK) cell differentiation, characterized by a loss of NKG2A in parallel with the acquisition of NKG2C, KIRs, and CD57 is stimulated by a number of virus infections,...
9.
Svensson A, Jakara E, Shestakov A, Eriksson K
Viral Immunol . 2010 Dec; 23(6):647-51. PMID: 21142451
We have evaluated the role of γ-secretase, which is a crucial component in the Notch-induced signaling cascade, on herpes simplex virus type 2 (HSV-2)-induced innate and acquired interferon responses in...
10.
Svensson A, Bergin A, Lowhagen G, Tunback P, Bellner L, Padyukov L, et al.
J Gen Virol . 2008 Aug; 89(Pt 9):2262-2268. PMID: 18753235
It was recently shown that the transcription factor T-bet is crucial for adequate innate and acquired immune responses to genital herpes simplex virus type 2 (HSV-2) infection in mice. To...