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Alexandra Pacheco-Benichou

Explore the profile of Alexandra Pacheco-Benichou including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 48
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Recent Articles
1.
Broudic N, Pacheco-Benichou A, Corbiere C, Baratte B, Robert T, Bach S, et al.
Pharmaceuticals (Basel) . 2024 Nov; 17(11). PMID: 39598364
In connection with previous work on V-shaped polycyclic thiazolo[5,4-]quinazolin-9-one and [5,4-]quinazoline derivatives that can modulate the activity of various kinases, the synthesis of straight thiazole-fused [4,5-] or [5,4-]quinazolin-8-ones and quinazoline...
2.
Broudic N, Pacheco-Benichou A, Fruit C, Besson T
Molecules . 2022 Dec; 27(23). PMID: 36500519
We report herein on a catalytic system involving palladium and copper to achieve the cyclization of -arylcyanothioformamides and the synthesis of 2-cyanobenzothiazoles. The C-H functionalization/intramolecular C-S bond formation reaction was...
3.
Elagib K, Brock A, Clementelli C, Mosoyan G, Delehanty L, Sahu R, et al.
J Clin Invest . 2022 Aug; 132(19). PMID: 35925681
Infantile (fetal and neonatal) megakaryocytes (Mks) have a distinct phenotype consisting of hyperproliferation, limited morphogenesis, and low platelet production capacity. These properties contribute to clinical problems that include thrombocytopenia in...
4.
Bhansali R, Rammohan M, Lee P, Laurent A, Wen Q, Suraneni P, et al.
J Clin Invest . 2021 Jan; 131(1). PMID: 33393494
DYRK1A is a serine/threonine kinase encoded on human chromosome 21 (HSA21) that has been implicated in several pathologies of Down syndrome (DS), including cognitive deficits and Alzheimer's disease. Although children...