Alexandra Montagner
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Explore the profile of Alexandra Montagner including associated specialties, affiliations and a list of published articles.
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59
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2146
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Recent Articles
1.
Fougerat A, Bruse J, Polizzi A, Montagner A, Guillou H, Wahli W
Prog Lipid Res
. 2024 Nov;
96:101303.
PMID: 39521352
Peroxisome proliferator-activated receptors (PPARs) constitute a small family of three nuclear receptors that act as lipid sensors, and thereby regulate the transcription of genes having key roles in hepatic and...
2.
Labour A, Lac M, Frassin L, Lair B, Murphy E, Maslo C, et al.
Cell Rep
. 2024 Aug;
43(8):114577.
PMID: 39096490
Growth and differentiation factor 15 (GDF15) has recently emerged as a weight loss and insulin-sensitizing factor. Growing evidence also supports a role for GDF15 as a physiological, exercise-induced stress signal....
3.
Schoeler M, Ellero-Simatos S, Birkner T, Mayneris-Perxachs J, Olsson L, Brolin H, et al.
Nat Commun
. 2023 Sep;
14(1):5329.
PMID: 37658064
Dietary lipids can affect metabolic health through gut microbiota-mediated mechanisms, but the influence of lipid-microbiota interaction on liver steatosis is largely unknown. We investigate the impact of dietary lipids on...
4.
Fabre A, Tramunt B, Montagner A, Mouly C, Riant E, Calmy M, et al.
Front Endocrinol (Lausanne)
. 2023 Aug;
14:1215947.
PMID: 37529599
Background: Estrogen Receptor α (ERα) is a significant modulator of energy balance and lipid/glucose metabolisms. Beyond the classical nuclear actions of the receptor, rapid activation of intracellular signaling pathways is...
5.
Karsenty C, Guilbeau-Frugier C, Genet G, Seguelas M, Alzieu P, Cazorla O, et al.
Elife
. 2023 Jan;
12.
PMID: 36649053
The rod-shaped adult cardiomyocyte (CM) harbors a unique architecture of its lateral surface with periodic crests, relying on the presence of subsarcolemmal mitochondria (SSM) with unknown role. Here, we investigated...
6.
Fougerat A, Schoiswohl G, Polizzi A, Regnier M, Wagner C, Smati S, et al.
Cell Rep
. 2022 Jun;
39(10):110910.
PMID: 35675775
In hepatocytes, peroxisome proliferator-activated receptor α (PPARα) orchestrates a genomic and metabolic response required for homeostasis during fasting. This includes the biosynthesis of ketone bodies and of fibroblast growth factor...
7.
Fougeray T, Polizzi A, Regnier M, Fougerat A, Ellero-Simatos S, Lippi Y, et al.
Cell Rep
. 2022 Apr;
39(2):110674.
PMID: 35417722
Liver physiology is circadian and sensitive to feeding and insulin. Food intake regulates insulin secretion and is a dominant signal for the liver clock. However, how much insulin contributes to...
8.
Personnaz J, Piccolo E, Dortignac A, Iacovoni J, Mariette J, Rocher V, et al.
Sci Adv
. 2022 Mar;
8(12):eabg9055.
PMID: 35333579
Dysregulations of lipid metabolism in the liver may trigger steatosis progression, leading to potentially severe clinical consequences such as nonalcoholic fatty liver diseases (NAFLDs). Molecular mechanisms underlying liver lipogenesis are...
9.
Tramunt B, Montagner A, Tan N, Gourdy P, Remignon H, Wahli W
Metabolites
. 2021 Aug;
11(8).
PMID: 34436443
The liver is a vital organ that sustains multiple functions beneficial for the whole organism. It is sexually dimorphic, presenting sex-biased gene expression with implications for the phenotypic differences between...
10.
Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, et al.
Gut
. 2021 Apr;
71(4):807-821.
PMID: 33903148
Objective: We evaluated the influence of sex on the pathophysiology of non-alcoholic fatty liver disease (NAFLD). We investigated diet-induced phenotypic responses to define sex-specific regulation between healthy liver and NAFLD...