Alexandra Maertens
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Explore the profile of Alexandra Maertens including associated specialties, affiliations and a list of published articles.
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46
Citations
618
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Recent Articles
1.
Maertens A, Brykman S, Hartung T, Gafita A, Bai H, Hoelzer D, et al.
Front Artif Intell
. 2024 Dec;
7:1400732.
PMID: 39717840
In response to the increasing significance of artificial intelligence (AI) in healthcare, there has been increased attention - including a Presidential executive order to create an AI Safety Institute -...
2.
Illingworth E, Rychlik K, Maertens A, Sille F
Toxicology
. 2024 Nov;
510:153988.
PMID: 39515575
Both tissue-resident macrophages and monocytes recruited from the bone marrow that transform into tissue-resident cells play critical roles in mediating homeostasis as well as in the pathology of inflammatory diseases....
3.
Hartung T, Maertens A, Luechtefeld T
ALTEX
. 2024 Oct;
41(4):567-587.
PMID: 39444208
The validation of new approach methods (NAMs) in toxicology faces significant challenges, including the integration of diverse data, selection of appropriate reference chemicals, and lengthy, resource-intensive consensus processes. This article...
4.
Gao Y, Mughal Z, Jaramillo-Villegas J, Corradi M, Borrel A, Lieberman B, et al.
ArXiv
. 2024 Sep;
PMID: 39253636
Researchers in biomedical research, public health and the life sciences often spend weeks or months discovering, accessing, curating, and integrating data from disparate sources, significantly delaying the onset of actual...
5.
Sille F, Busquet F, Fitzpatrick S, Herrmann K, Leenhouts-Martin L, Luechtefeld T, et al.
ALTEX
. 2024 Jul;
41(3):344-362.
PMID: 39016082
The Human Exposome Project aims to revolutionize our understanding of how environmental exposures affect human health by systematically cataloging and analyzing the myriad exposures individuals encounter throughout their lives. This...
6.
Paller C, Tukachinsky H, Maertens A, Decker B, Sampson J, Cheadle J, et al.
JCO Precis Oncol
. 2024 Feb;
8:e2300251.
PMID: 38394468
Purpose: Biallelic germline pathogenic variants of the base excision repair (BER) pathway gene predispose to colorectal cancer (CRC) and other cancers. The possible association of heterozygous variants with broader cancer...
7.
Maertens A, Antignac E, Benfenati E, Bloch D, Fritsche E, Hoffmann S, et al.
ALTEX
. 2024 Jan;
41(2):273-281.
PMID: 38215352
Both because of the shortcomings of existing risk assessment methodologies, as well as newly available tools to predict hazard and risk with machine learning approaches, there has been an emerging...
8.
Maertens A, Luechtefeld T, Knight J, Hartung T
ALTEX
. 2024 Jan;
41(1):3-19.
PMID: 38194639
Green toxicology is marching chemistry into the 21st century. This emerging framework will transform how chemical safety is evaluated by incorporating evaluation of the hazards, exposures, and risks associated with...
9.
Kincaid B, Piechota P, Golden E, Maertens M, Hartung T, Maertens A
Front Toxicol
. 2023 Nov;
5:1216802.
PMID: 37908592
The positive identification of xenobiotics and their metabolites in human biosamples is an integral aspect of exposomics research, yet challenges in compound annotation and identification continue to limit the feasibility...
10.
Illingworth E, Maertens A, Sille F
bioRxiv
. 2023 Aug;
PMID: 37546857
Both tissue-resident macrophages and monocytes recruited from the bone marrow that transform into tissue-resident cells play critical roles in mediating homeostasis as well as in the pathology of inflammatory diseases....