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Alexandra L Scharr

Explore the profile of Alexandra L Scharr including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 25
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Recent Articles
1.
Scharr A, O Maoileidigh D, Ricci A
J Neurosci . 2023 Feb; 43(12):2053-2074. PMID: 36746628
The hair bundle is the universal mechanosensory organelle of auditory, vestibular, and lateral-line systems. A bundle comprises mechanically coupled stereocilia, whose displacements in response to stimulation activate a receptor current....
2.
Timon-Gomez A, Scharr A, Wong N, Ni E, Roy A, Liu M, et al.
Elife . 2022 Oct; 11. PMID: 36255054
Mammalian carotid body arterial chemoreceptors function as an early warning system for hypoxia, triggering acute life-saving arousal and cardiorespiratory reflexes. To serve this role, carotid body glomus cells are highly...
3.
Peng A, Scharr A, Caprara G, Nettles D, Steele C, Ricci A
Front Cell Dev Biol . 2021 Sep; 9:725101. PMID: 34513845
Hair cell mechanosensitivity resides in the sensory hair bundle, an apical protrusion of actin-filled stereocilia arranged in a staircase pattern. Hair bundle deflection activates mechano-electric transduction (MET) ion channels located...
4.
Effertz T, Scharr A, Ricci A
Pflugers Arch . 2014 Sep; 467(1):73-84. PMID: 25241775
Identification of the auditory hair cell mechano-electrical transduction (hcMET) channel has been a major focus in the hearing research field since the 1980s when direct mechanical gating of a transduction...
5.
Scharr A, Mooney T, Schweizer F, Ketten D
Biol Bull . 2014 Sep; 227(1):51-60. PMID: 25216502
Squid are a significant component of the marine biomass and are a long-established model organism in experimental neurophysiology. The squid statocyst senses linear and angular acceleration and is the best...