Alexandra Kavun
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Explore the profile of Alexandra Kavun including associated specialties, affiliations and a list of published articles.
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10
Citations
13
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Recent Articles
1.
Ivanov M, Lebedeva A, Belova E, Grigoreva T, Veselovsky E, Kavun A, et al.
J Clin Lab Anal
. 2025 Mar;
:e70008.
PMID: 40056420
Background: Next-generation sequencing (NGS) is increasingly integrated into cancer patient management, necessitating cost-effective, reliable tests for companion diagnostics. We present the validation of the Solo-test Driver panel, a custom NGS...
2.
Kravchuk D, Lebedeva A, Kuznetsova O, Kavun A, Taraskina A, Belova E, et al.
Front Immunol
. 2025 Feb;
16:1492296.
PMID: 39975556
Microsatellite instability (MSI) is a widely studied molecular signature, which is associated with long-term benefit in patients treated with immune checkpoint inhibitor therapy. This approach has been proven to be...
3.
Veselovsky E, Lebedeva A, Kuznetsova O, Kravchuk D, Belova E, Taraskina A, et al.
Sci Rep
. 2024 Oct;
14(1):23454.
PMID: 39379462
Analysis of serial liquid biopsy (LB) samples has been found to be a promising approach for the monitoring of tumor dynamics in the course of therapy for patients with colorectal...
4.
Lebedeva A, Belova E, Kavun A, Taraskina A, Bartoletti M, Bieche I, et al.
Mol Diagn Ther
. 2024 Oct;
29(1):91-101.
PMID: 39368036
Background: The widespread use of next-generation sequencing in clinical practice has contributed to the accumulation of a large number of genomic findings associated with targeted therapy; therefore, the problem of...
5.
Babayan A, Ledin E, Lebedeva A, Kuznetsova O, Kravchuk D, Grigoreva T, et al.
Immunotherapy
. 2024 Jul;
16(13):853-858.
PMID: 39041702
Microsatellite instability (MSI) is an important biomarker in cancer. While routine methods can detect MSI in certain tumor types, in other tumor types the results may be incorrect due to...
6.
Lebedeva A, Veselovsky E, Kavun A, Belova E, Grigoreva T, Orlov P, et al.
World J Oncol
. 2024 Jul;
15(4):562-578.
PMID: 38993246
Background: Testing for homologous recombination deficiency (HRD) mutations is pivotal to assess individual risk, to proact preventive measures in healthy carriers and to tailor treatments for cancer patients. Increasing prominence...
7.
Lebedeva A, Kuznetsova O, Ivanov M, Kavun A, Veselovsky E, Belova E, et al.
Heliyon
. 2024 May;
10(9):e30303.
PMID: 38707351
Genomic profiling, or molecular profiling of the tumor, is becoming a key component of therapeutic decision making in clinical oncology, and is typically carried out via next generation sequencing. However,...
8.
Polyanskaya E, Lebedeva A, Kuznetsova O, Belova E, Kavun A, Ivanov M, et al.
Front Oncol
. 2023 Nov;
13:1245547.
PMID: 38023256
Colorectal cancer (CRC) is currently one of the most common tumor types diagnosed worldwide. In the early stages, the disease responds well to surgical and chemotherapeutic treatment, but in the...
9.
Kuznetsova O, Lebedeva A, Kavun A, Belova E, Fedyanin M, Mileyko V, et al.
Am J Transl Res
. 2023 Oct;
15(9):5785-5790.
PMID: 37854204
Despite the existence of effective first and second line therapy options for patients with colorectal cancer, heavily treated patients have limited additional therapies. Genomic profiling is a promising tool for...
10.
Yakushina V, Kavun A, Veselovsky E, Grigoreva T, Belova E, Lebedeva A, et al.
JCO Precis Oncol
. 2023 Jun;
7:e2300010.
PMID: 37315263
No abstract available.