Alexandra Grubman
Overview
Explore the profile of Alexandra Grubman including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
38
Citations
1451
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Scoyni F, Giudice L, Vaananen M, Downes N, Korhonen P, Choo X, et al.
Alzheimers Dement
. 2023 Oct;
20(2):954-974.
PMID: 37828821
Introduction: Alzheimer's disease (AD) is a neurodegenerative disease and the main cause of dementia in the elderly. AD pathology is characterized by accumulation of microglia around the beta-amyloid (Aβ) plaques...
2.
Zhou Y, Xie L, Schroder J, Schuster I, Nakai M, Sun G, et al.
J Neurosci
. 2023 Aug;
43(37):6460-6475.
PMID: 37596052
Alzheimer's disease (AD) is a neurodegenerative disorder with poorly understood etiology. AD has several similarities with other "Western lifestyle" inflammatory diseases, where the gut microbiome and immune pathways have been...
3.
Leinenga G, Bodea L, Schroder J, Sun G, Zhou Y, Song J, et al.
Bioeng Transl Med
. 2023 Jan;
8(1):e10329.
PMID: 36684089
Transcranial scanning ultrasound combined with intravenously injected microbubbles (SUS) has been shown to transiently open the blood-brain barrier and reduce the amyloid-β (Aβ) pathology in the APP23 mouse model of...
4.
Chear S, Perry S, Wilson R, Bindoff A, Talbot J, Ware T, et al.
Dis Model Mech
. 2022 Dec;
15(12).
PMID: 36453132
CLN3 disease is a lysosomal storage disorder associated with fatal neurodegeneration that is caused by mutations in CLN3, with most affected individuals carrying at least one allele with a 966 ...
5.
Choo X, McInnes L, Grubman A, Wasielewska J, Belaya I, Burrows E, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142627
Neuroinflammation has a major role in several brain disorders including Alzheimer's disease (AD), yet at present there are no effective anti-neuroinflammatory therapeutics available. Copper(II) complexes of bis(thiosemicarbazones) (Cu(gtsm) and Cu(atsm))...
6.
Chothani S, Adami E, Widjaja A, Langley S, Viswanathan S, Pua C, et al.
Mol Cell
. 2022 Jul;
82(15):2885-2899.e8.
PMID: 35841888
Translated small open reading frames (smORFs) can have important regulatory roles and encode microproteins, yet their genome-wide identification has been challenging. We determined the ribosome locations across six primary human...
7.
Grubman A, Choo X, Chew G, Ouyang J, Sun G, Croft N, et al.
Nat Commun
. 2021 May;
12(1):3015.
PMID: 34021136
The role of microglia cells in Alzheimer's disease (AD) is well recognized, however their molecular and functional diversity remain unclear. Here, we isolated amyloid plaque-containing (using labelling with methoxy-XO4, XO4)...
8.
Liu X, Ouyang J, Rossello F, Tan J, Davidson K, Valdes D, et al.
Nature
. 2020 Sep;
586(7827):101-107.
PMID: 32939092
The reprogramming of human somatic cells to primed or naive induced pluripotent stem cells recapitulates the stages of early embryonic development. The molecular mechanism that underpins these reprogramming processes remains...
9.
Belaya I, Ivanova M, Sorvari A, Ilicic M, Loppi S, Koivisto H, et al.
J Neuroinflammation
. 2020 Sep;
17(1):271.
PMID: 32933545
Background: Increased physical exercise improves cognitive function and reduces pathology associated with Alzheimer's disease (AD). However, the mechanisms underlying the beneficial effects of exercise in AD on the level of...
10.
Chew S, Lampinen R, Saveleva L, Korhonen P, Mikhailov N, Grubman A, et al.
Part Fibre Toxicol
. 2020 Jun;
17(1):18.
PMID: 32487172
Background: The adverse effects of air pollutants including particulate matter (PM) on the central nervous system is increasingly reported by epidemiological, animal and post-mortem studies in the last decade. Oxidative...