Alexandra Andrieux
Overview
Explore the profile of Alexandra Andrieux including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
243
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Recent Articles
1.
Theurillat I, Hendriks I, Cossec J, Andrieux A, Nielsen M, Dejean A
Cell Rep
. 2020 Oct;
33(1):108251.
PMID: 33027645
No abstract available.
2.
Lopez I, Chalatsi E, Ellenbroek S, Andrieux A, Roux P, Cerapio J, et al.
Oncogene
. 2020 Sep;
39(43):6692-6703.
PMID: 32948837
Sumoylation is an essential posttranslational modification in eukaryotes that has emerged as an important pathway in oncogenic processes. Most human cancers display hyperactivated sumoylation and many cancer cells are remarkably...
3.
Theurillat I, Hendriks I, Cossec J, Andrieux A, Nielsen M, Dejean A
Cell Rep
. 2020 Sep;
32(11):108146.
PMID: 32937131
Post-translational modification by SUMO is a key regulator of cell identity. In mouse embryonic fibroblasts (MEFs), SUMO impedes reprogramming to pluripotency, while in embryonic stem cells (ESCs), it represses the...
4.
Agarwal N, Taberner F, Rangel Rojas D, Moroni M, Omberbasic D, Njoo C, et al.
Neuron
. 2020 Aug;
107(6):1141-1159.e7.
PMID: 32735781
Diabetic peripheral neuropathy (DPN) is a highly frequent and debilitating clinical complication of diabetes that lacks therapies. Cellular oxidative stress regulates post-translational modifications, including SUMOylation. Here, using unbiased screens, we...
5.
Rodriguez A, Briley S, Patton B, Tripurani S, Rajapakshe K, Coarfa C, et al.
Development
. 2019 Nov;
146(23).
PMID: 31704792
The number and quality of oocytes within the ovarian reserve largely determines fertility and reproductive lifespan in mammals. An oocyte-specific transcription factor cascade controls oocyte development, and some of these...
6.
Cossec J, Theurillat I, Chica C, Bua Aguin S, Gaume X, Andrieux A, et al.
Cell Stem Cell
. 2018 Nov;
23(5):742-757.e8.
PMID: 30401455
Understanding general principles that safeguard cellular identity should reveal critical insights into common mechanisms underlying specification of varied cell types. Here, we show that SUMO modification acts to stabilize cell...
7.
Lapaquette P, Fritah S, Lhocine N, Andrieux A, Nigro G, Mounier J, et al.
Elife
. 2017 Dec;
6.
PMID: 29231810
Disruption of the sumoylation/desumoylation equilibrium is associated with several disease states such as cancer and infections, however the mechanisms regulating the global SUMO balance remain poorly defined. Here, we show...
8.
Fritah S, Lhocine N, Golebiowski F, Mounier J, Andrieux A, Jouvion G, et al.
EMBO Rep
. 2014 Aug;
15(9):965-72.
PMID: 25097252
Shigella flexneri, the etiological agent of bacillary dysentery, invades the human colonic epithelium and causes its massive inflammatory destruction. Little is known about the post-translational modifications implicated in regulating the...
9.
Sahin U, Lapaquette P, Andrieux A, Faure G, Dejean A
PLoS One
. 2014 Jul;
9(7):e102957.
PMID: 25036361
Gene silencing by small RNAs has emerged as a powerful post-transcriptional regulator of gene expression, however processes underlying regulation of the small RNA pathway in vivo are still largely elusive....
10.
Demarque M, Nacerddine K, Neyret-Kahn H, Andrieux A, Danenberg E, Jouvion G, et al.
Gastroenterology
. 2010 Oct;
140(1):286-96.
PMID: 20951138
Background & Aims: Small ubiquitin-like modifiers (SUMOs) are attached to other proteins to regulate their function (sumoylation). We investigated the role of Ubc9, which covalently attaches SUMOs to proteins, in...