Alexandra A C Newman
Overview
Explore the profile of Alexandra A C Newman including associated specialties, affiliations and a list of published articles.
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13
Citations
1127
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Recent Articles
1.
Newman A, Dalman J, Moore K
Arterioscler Thromb Vasc Biol
. 2025 Jan;
45(3):359-371.
PMID: 39781742
The field of cardio-oncology has traditionally focused on the impact of cancer and its therapies on cardiovascular health. Mounting clinical and preclinical evidence, however, indicates that the reverse may also...
2.
Schlegel M, Cyr Y, Newman A, Schreyer K, Barcia Duran J, Sharma M, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(44):e2412690121.
PMID: 39436659
Atherosclerosis results from lipid-driven inflammation of the arterial wall that fails to resolve. Imbalances in macrophage accumulation and function, including diminished migratory capacity and defective efferocytosis, fuel maladaptive inflammation and...
3.
Newman A, Von Itter R, Moore K
Circulation
. 2024 May;
149(22):1749-1751.
PMID: 38805582
No abstract available.
4.
Cyr Y, Bozal F, Barcia Duran J, Newman A, Amadori L, Smyrnis P, et al.
Proc Natl Acad Sci U S A
. 2024 Apr;
121(15):e2400675121.
PMID: 38564634
Atherosclerosis is fueled by a failure to resolve lipid-driven inflammation within the vasculature that drives plaque formation. Therapeutic approaches to reverse atherosclerotic inflammation are needed to address the rising global...
5.
Newman A, Cyr Y, Moore K
Eur Heart J
. 2022 May;
43(19):1878-1880.
PMID: 35567566
No abstract available.
6.
Hartmann F, Gorski D, Newman A, Homann S, Petz A, Owsiany K, et al.
Circ Res
. 2021 Oct;
129(11):992-1005.
PMID: 34615369
[Figure: see text].
7.
Barrett T, Corr E, van Solingen C, Schlamp F, Brown E, Koelwyn G, et al.
Cell Rep
. 2021 Sep;
36(10):109595.
PMID: 34496250
Psychological stress (PS) is associated with systemic inflammation and accelerates inflammatory disease progression (e.g., atherosclerosis). The mechanisms underlying stress-mediated inflammation and future health risk are poorly understood. Monocytes are key...
8.
Schlegel M, Sharma M, Brown E, Newman A, Cyr Y, Afonso M, et al.
Circ Res
. 2021 Jul;
129(5):530-546.
PMID: 34289717
Rationale: Therapeutic efforts to decrease atherosclerotic cardiovascular disease risk have focused largely on reducing atherogenic lipoproteins, yet lipid-lowering therapies alone are insufficient to fully regress plaque burden. We postulate that...
9.
Newman A, Serbulea V, Baylis R, Shankman L, Bradley X, Alencar G, et al.
Nat Metab
. 2021 Feb;
3(2):166-181.
PMID: 33619382
Stable atherosclerotic plaques are characterized by a thick, extracellular matrix-rich fibrous cap populated by protective ACTA2 myofibroblast (MF)-like cells, assumed to be almost exclusively derived from smooth muscle cells (SMCs)....
10.
Koelwyn G, Newman A, Afonso M, van Solingen C, Corr E, Brown E, et al.
Nat Med
. 2020 Jul;
26(9):1452-1458.
PMID: 32661390
Disruption of systemic homeostasis by either chronic or acute stressors, such as obesity or surgery, alters cancer pathogenesis. Patients with cancer, particularly those with breast cancer, can be at increased...