Alexander W Drong
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Explore the profile of Alexander W Drong including associated specialties, affiliations and a list of published articles.
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12
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4035
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Recent Articles
1.
Solovyov A, Behr J, Hoyos D, Banks E, Drong A, Thornlow B, et al.
Nat Commun
. 2025 Feb;
16(1):2049.
PMID: 40021663
Somatic mobilization of LINE-1 (L1) has been implicated in cancer etiology. We analyzed a recent TCGA data release comprised of nearly 5000 pan-cancer paired tumor-normal whole-genome sequencing (WGS) samples and...
2.
Cortes-Lopez M, Chamely P, Hawkins A, Stanley R, Swett A, Ganesan S, et al.
Cell Stem Cell
. 2023 Aug;
30(9):1262-1281.e8.
PMID: 37582363
RNA splicing factors are recurrently mutated in clonal blood disorders, but the impact of dysregulated splicing in hematopoiesis remains unclear. To overcome technical limitations, we integrated genotyping of transcriptomes (GoT)...
3.
Rahmioglu N, Drong A, Lockstone H, Tapmeier T, Hellner K, Saare M, et al.
Epigenetics
. 2017 Nov;
12(10):897-908.
PMID: 29099281
Genome-wide association studies in the fields of reproductive medicine and endocrinology are yielding robust genetic variants associated with disease. Integrated genomic, transcriptomic, and epigenomic molecular profiling studies are common methodologies...
4.
Lehne B, Drong A, Loh M, Zhang W, Scott W, Tan S, et al.
Genome Biol
. 2016 Apr;
17:73.
PMID: 27103459
No abstract available.
5.
Lu Y, Day F, Gustafsson S, Buchkovich M, Na J, Bataille V, et al.
Nat Commun
. 2016 Feb;
7:10495.
PMID: 26833246
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up...
6.
Kilpelainen T, Martin Carli J, Skowronski A, Sun Q, Kriebel J, Feitosa M, et al.
Nat Commun
. 2016 Feb;
7:10494.
PMID: 26833098
Leptin is an adipocyte-secreted hormone, the circulating levels of which correlate closely with overall adiposity. Although rare mutations in the leptin (LEP) gene are well known to cause leptin deficiency...
7.
Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, et al.
Nat Genet
. 2015 Sep;
47(11):1282-1293.
PMID: 26390057
We carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry. We find genetic...
8.
Karaderi T, Drong A, Lindgren C
Curr Diab Rep
. 2015 Sep;
15(10):83.
PMID: 26363598
Obesity and type 2 diabetes (T2D) are common and complex metabolic diseases, which are caused by an interchange between environmental and genetic factors. Recently, a number of large-scale genome-wide association...
9.
Lehne B, Drong A, Loh M, Zhang W, Scott W, Tan S, et al.
Genome Biol
. 2015 Apr;
16:37.
PMID: 25853392
DNA methylation plays a fundamental role in the regulation of the genome, but the optimal strategy for analysis of genome-wide DNA methylation data remains to be determined. We developed a...
10.
Locke A, Kahali B, Berndt S, Justice A, Pers T, Day F, et al.
Nature
. 2015 Feb;
518(7538):197-206.
PMID: 25673413
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index...