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Alexander W Bell

Explore the profile of Alexander W Bell including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 835
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Recent Articles
1.
Ouellette S, Bell A, van Oostrum J, Bergeron J
Mol Cell Proteomics . 2009 Jun; 8(6):1450-2. PMID: 19494340
No abstract available.
2.
Bell A, Deutsch E, Au C, Kearney R, Beavis R, Sechi S, et al.
Nat Methods . 2009 May; 6(6):423-30. PMID: 19448641
We performed a test sample study to try to identify errors leading to irreproducibility, including incompleteness of peptide sampling, in liquid chromatography-mass spectrometry-based proteomics. We distributed an equimolar test sample,...
3.
Yanofsky C, Kearney R, Lesimple S, Bergeron J, Boismenu D, Carrillo B, et al.
Annu Int Conf IEEE Eng Med Biol Soc . 2009 Jan; 2008:3775-8. PMID: 19163533
In high-throughput proteomics, one promising approach presently being explored is the Accurate Mass and Time (AMT) tag approach, in which reversed-phase liquid chromatography coupled to high accuracy mass spectrometry provide...
4.
Yanofsky C, Kearney R, Lesimple S, Bergeron J, Boismenu D, Carrillo B, et al.
Annu Int Conf IEEE Eng Med Biol Soc . 2007 Nov; 2007:1221-4. PMID: 18002183
In high-throughput mass spectrometry-based proteomics, it is necessary to employ separations to reduce sample complexity prior to mass spectrometric peptide identification. Interest has begun to focus on using information from...
5.
Bell A, Nilsson T, Kearney R, Bergeron J
Nat Methods . 2007 Sep; 4(10):783-4. PMID: 17901866
Mass spectrometry has come into its own as an extremely powerful tool for the study of whole proteomes. So why are not more cell biologists embracing it with open arms?
6.
Au C, Bell A, Gilchrist A, Hiding J, Nilsson T, Bergeron J
Curr Opin Cell Biol . 2007 Aug; 19(4):376-85. PMID: 17689063
The elucidation of a complete, accurate, and permanent representation of the proteome of the mammalian cell may be achievable piecemeal by an organellar based approach. The small volume of organelles...
7.
Liu J, Bell A, Bergeron J, Yanofsky C, Carrillo B, Beaudrie C, et al.
Proteome Sci . 2007 Jan; 5:3. PMID: 17227583
Background: Tandem mass spectrometry followed by database search is currently the predominant technology for peptide sequencing in shotgun proteomics experiments. Most methods compare experimentally observed spectra to the theoretical spectra...
8.
Gilchrist A, Au C, Hiding J, Bell A, Fernandez-Rodriguez J, Lesimple S, et al.
Cell . 2006 Dec; 127(6):1265-81. PMID: 17174899
We report more than 1400 proteins of the secretory-pathway proteome and provide spatial information on the relative presence of each protein in the rough and smooth ER Golgi cisternae and...
9.
Elvira G, Wasiak S, Blandford V, Tong X, Serrano A, Fan X, et al.
Mol Cell Proteomics . 2005 Dec; 5(4):635-51. PMID: 16352523
In brain, mRNAs are transported from the cell body to the processes, allowing for local protein translation at sites distant from the nucleus. Using subcellular fractionation, we isolated a fraction...
10.
Yanofsky C, Bell A, Lesimple S, Morales F, Lam T, Blakney G, et al.
Anal Chem . 2005 Nov; 77(22):7246-54. PMID: 16285672
In high-throughput proteomics, a promising current approach is the use of liquid chromatography coupled to Fourier transform ion cyclotron resonance mass spectrometry (LC-FTICR-MS) of tryptic peptides from complex mixtures of...