Alexander T Florence
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Explore the profile of Alexander T Florence including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
402
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Recent Articles
21.
Jaitely V, Karatas A, Florence A
Int J Pharm
. 2008 Mar;
354(1-2):168-73.
PMID: 18342462
Water-immiscible room temperature ionic liquids (RTILs) have a largely unexplored potential as pharmaceutical solvents and reservoirs. This paper explores some relevant properties of the hexafluorophosphate (PF6(-)) salts of butyl, hexyl...
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Ribeiro S, Rijpkema S, Durrani Z, Florence A
Int J Pharm
. 2007 Jan;
331(2):228-32.
PMID: 17258876
Dendriplexes, complexes of dendrons and condensed plasmids containing the gene for protective antigen (PA) of Bacillus anthracis, were encapsulated in poly-lactide-co-glycolide (PLGA) particles using the double emulsion method. The two...
25.
Suitthimeathegorn O, Turton J, Mizuuchi H, Florence A
Int J Pharm
. 2007 Jan;
331(2):204-10.
PMID: 17250983
Non-aqueous or oil-in-oil emulsions may be used as reservoirs to deliver lipophilic or hydrolytically unstable drugs. Emulsions of castor oil-in-silicone oil (co/so) release drugs slowly in vitro. To investigate the...
26.
Ruenraroengsak P, Al-Jamal K, Hartell N, Braeckmans K, De Smedt S, Florence A
Int J Pharm
. 2007 Jan;
331(2):215-9.
PMID: 17234370
Macromolecular crowding and the presence of organelles in the cytosol present barriers to particle mobility, such that it is unclear how nano-carriers can deliver their active agents to the nucleus....
27.
Al-Jamal K, Ruenraroengsak P, Hartell N, Florence A
J Drug Target
. 2006 Nov;
14(6):405-12.
PMID: 17092840
Dendrimers, spherical or quasi-spherical synthetic polymers in the nano-size range, have found useful applications as prospective carriers in drug and gene delivery. The investigation of dendrimer uptake by cells has...
28.
Bayele H, Ramaswamy C, Wilderspin A, S Srai K, Toth I, Florence A
J Pharm Sci
. 2006 Apr;
95(6):1227-37.
PMID: 16639724
We investigated the potential of a new family of lipidic peptide dendrimers in protein transduction into cultured cells. Dendrimer-protein interaction was determined by gel retardation assays using purified recombinant protein....
29.
Al-Jamal K, Ramaswamy C, Florence A
Adv Drug Deliv Rev
. 2005 Nov;
57(15):2238-70.
PMID: 16310885
This paper reviews aspects of the association of dendrons and dendrimers into a variety of supramolecular structures. There is such a wide range of primary dendron and dendrimer chemistries that...
30.
Nasseri B, Florence A
Int J Pharm
. 2005 Jun;
298(2):372-7.
PMID: 15985348
Lipid nanotubes or "tethers" can be formed from liposomes or niosomes, pulled from the parent vesicles by micromanipulation. The tethers are cylindrical multibilayer tubes. Here, we describe the movement of...