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Alexander T Florence

Explore the profile of Alexander T Florence including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 402
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Recent Articles
11.
Florence A
J Control Release . 2012 Apr; 164(2):115-24. PMID: 22484196
In comparison to the complexities of the body, its organs, its normal and aberrant cells, many nanoparticles will appear to be relatively simple objects. This view is deceptive because the...
12.
Florence A
J Control Release . 2011 Nov; 161(2):399-402. PMID: 22100439
This paper briefly discusses reductionism as a process for dissecting the complexities of drug targeting mediated by nanoparticulate carriers. While reductionism has been said to have been a drawback to...
13.
Florence A, Lee V
Int J Pharm . 2011 May; 415(1-2):29-33. PMID: 21565262
No abstract available.
14.
Lee V, Florence A
Int J Pharm . 2011 Mar; 415(1-2):1. PMID: 21439365
No abstract available.
15.
Jaitely V, Mizuuchi H, Florence A
J Drug Target . 2010 Nov; 18(10):787-93. PMID: 21047272
Room temperature ionic liquids (RTILs), salts which are liquid at room temperature, may be water-soluble or water immiscible, depending on the combination of cation and anion. They are efficient solvents...
16.
Al-Obaidi H, Nasseri B, Florence A
J Drug Target . 2010 Oct; 18(10):821-30. PMID: 21029030
Microparticles and nanoparticles used in drug delivery frequently depend on their movement in confined spaces such as cells. Liposomes containing small numbers of 1-µm diameter polystyrene particles were used to...
17.
Ruenraroengsak P, Florence A
J Drug Target . 2010 Oct; 18(10):803-11. PMID: 20932230
Gene delivery systems face the problem not only of the route toward the cell and tissues in question, but also of the molecularly crowded environment of both the cytoplasm and...
18.
Florence A
Int J Pharm . 2010 Jul; 398(1-2):246. PMID: 20609424
No abstract available.
19.
Al-Jamal K, Al-Jamal W, Akerman S, Podesta J, Yilmazer A, Turton J, et al.
Proc Natl Acad Sci U S A . 2010 Feb; 107(9):3966-71. PMID: 20150514
This study describes the previously unreported intrinsic capacity of poly-L-lysine (PLL) sixth generation (G(6)) dendrimer molecules to exhibit systemic antiangiogenic activity that could lead to solid tumor growth arrest. The...
20.
Ruenraroengsak P, Cook J, Florence A
J Control Release . 2009 Nov; 141(3):265-76. PMID: 19895862
This review considers some of the obstacles to successful drug targeting and delivery of therapeutic agents to desired target sites in the body, in the context of the sometimes overblown...