Alexander R Pelletier
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Explore the profile of Alexander R Pelletier including associated specialties, affiliations and a list of published articles.
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10
Citations
114
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Recent Articles
1.
Pelletier A, Villamarin F, Campos-Silva J, Scabin A, Doig L, Jardine T
Sci Total Environ
. 2024 Dec;
958():178069.
PMID: 39700991
Trace elements play diverse roles in animal physiology ranging from essential micronutrients to potent toxicants. Despite animals accumulating many trace elements through their diets, relationships between trophic positions and biological...
2.
Missing Values in Longitudinal Proteome Dynamics Studies: Making a Case for Data Multiple Imputation
Yan Y, Sankar B, Mirza B, Ng D, Pelletier A, Huang S, et al.
J Proteome Res
. 2024 Aug;
23(9):4151-4162.
PMID: 39189460
Temporal proteomics data sets are often confounded by the challenges of missing values. These missing data points, in a time-series context, can lead to fluctuations in measurements or the omission...
3.
Pelletier A, Steinecke D, Sigdel D, Adam I, Caufield J, Guevara-Gonzalez V, et al.
J Vis Exp
. 2023 Oct;
(200).
PMID: 37902366
The rapidly increasing and vast quantities of biomedical reports, each containing numerous entities and rich information, represent a rich resource for biomedical text-mining applications. These tools enable investigators to integrate,...
4.
Yan Y, Jiang J, Fu M, Wang D, Pelletier A, Sigdel D, et al.
Cell Rep Methods
. 2023 Apr;
3(3):100430.
PMID: 37056379
We present a deep-learning-based platform, MIND-S, for protein post-translational modification (PTM) predictions. MIND-S employs a multi-head attention and graph neural network and assembles a 15-fold ensemble model in a multi-label...
5.
Robichaud S, Fairman G, Vijithakumar V, Mak E, Cook D, Pelletier A, et al.
Autophagy
. 2021 Feb;
17(11):3671-3689.
PMID: 33590792
Macrophage autophagy is a highly anti-atherogenic process that promotes the catabolism of cytosolic lipid droplets (LDs) to maintain cellular lipid homeostasis. Selective autophagy relies on tags such as ubiquitin and...
6.
Pelletier A, Chung Y, Ning Z, Wong N, Figeys D, Lavallee-Adam M
J Am Soc Mass Spectrom
. 2020 Jun;
31(7):1459-1472.
PMID: 32510216
Mass spectrometry-based proteomics technologies are prime methods for the high-throughput identification of proteins in complex biological samples. Nevertheless, there are still technical limitations that hinder the ability of mass spectrometry...
7.
Chung N, Choi H, Wang D, Mirza B, Pelletier A, Sigdel D, et al.
J Mol Cell Cardiol
. 2020 Jun;
145:54-58.
PMID: 32504647
Objective: During cardiovascular disease progression, molecular systems of myocardium (e.g., a proteome) undergo diverse and distinct changes. Dynamic, temporally-regulated alterations of individual molecules underlie the collective response of the heart...
8.
McClatchy D, Yu N, Martinez-Bartolome S, Patel R, Pelletier A, Lavalle-Adam M, et al.
ACS Chem Neurosci
. 2018 Jul;
9(12):3072-3085.
PMID: 30053369
Kinases are a major clinical target for human diseases. Identifying the proteins that interact with kinases in vivo will provide information on unreported substrates and will potentially lead to more...
9.
Pelletier A, Castello L, Zhulidov A, Gurtovaya T, Robarts R, Holmes R, et al.
Environ Sci Technol
. 2017 Oct;
51(22):13436-13442.
PMID: 29083154
Current understanding of mercury (Hg) dynamics in the Arctic is hampered by a lack of data in the Russian Arctic region, which comprises about half of the entire Arctic watershed....
10.
Kroll K, Mokaram N, Pelletier A, Frankhouser D, Westphal M, Stump P, et al.
Cancer Inform
. 2014 Nov;
13(Suppl 3):7-14.
PMID: 25368506
QuaCRS (Quality Control for RNA-Seq) is an integrated, simplified quality control (QC) system for RNA-seq data that allows easy execution of several open-source QC tools, aggregation of their output, and...