Alexander R Ochman
Overview
Explore the profile of Alexander R Ochman including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
64
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0
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Recent Articles
1.
Ochman A, Riesbeck M, Corbisiero R
HeartRhythm Case Rep
. 2021 Jul;
7(7):433-435.
PMID: 34307022
No abstract available.
2.
Kaur Z, Ochman A, Mayer J, Gelfanov V, DiMarchi R
ACS Chem Biol
. 2013 Jun;
8(8):1822-9.
PMID: 23730814
A series of novel, single chain insulin analogs containing polyethylene glycol based connecting segments were synthesized by native chemical ligation and tested for biological activity. While the full length single...
3.
Saporito M, Ochman A, Lipinski C, Handler J, Reaume A
J Pharmacol Exp Ther
. 2012 Apr;
342(1):15-22.
PMID: 22473614
2(1H)-pyrimidinone,5-(3-methylphenoxy) (MLR-1023) is a candidate for the treatment of type 2 diabetes. The current studies were aimed at determining the mechanism by which MLR-1023 mediates glycemic control. In these studies,...
4.
Ochman A, Lipinski C, Handler J, Reaume A, Saporito M
J Pharmacol Exp Ther
. 2012 Mar;
342(1):23-32.
PMID: 22431203
MLR-1023 [Tolimidone; CP-26154; 2(1H)-pyrimidinone, 5-(3-methylphenoxy)] is an allosteric Lyn kinase activator that reduces blood glucose levels in mice subjected to an oral glucose tolerance test (J Pharmacol Exp Ther 342:15-22,...
5.
Shetty R, Lee Y, Liu B, Husain A, Joseph R, Lu Y, et al.
J Med Chem
. 2010 Dec;
54(1):179-200.
PMID: 21126027
The synthesis and optimization of a series of orally bioavailable 1-(1H-indol-4-yl)-3,5-disubstituted benzene analogues as antimitotic agents are described. A functionalized dibromobenzene intermediate was used as a key scaffold, which when...
6.
Stewart S, Querec T, Ochman A, Gruver B, Bao R, Babb J, et al.
Cancer Res
. 2004 Nov;
64(22):8177-83.
PMID: 15548682
Animal models of ovarian cancer are crucial for understanding the pathogenesis of the disease and for testing new treatment strategies. A model of ovarian carcinogenesis in the rat was modified...