Alexander R Guimaraes
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Explore the profile of Alexander R Guimaraes including associated specialties, affiliations and a list of published articles.
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80
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3981
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Recent Articles
1.
Kong B, Stommel J, Keck J, Kilburn D, Streblow A, Egger J, et al.
JCO Precis Oncol
. 2024 Jun;
8:e2300686.
PMID: 38905574
Case report of a HER2-expressed ovarian clear cell carcinoma with exceptional response to trastuzumab deruxtecan.
2.
McCarthy G, Di Niro R, Finan J, Jain A, Guo Y, Wyatt C, et al.
NAR Cancer
. 2023 Apr;
5(2):zcad016.
PMID: 37089813
Stromal cells promote extensive fibrosis in pancreatic ductal adenocarcinoma (PDAC), which is associated with poor prognosis and therapeutic resistance. We report here for the first time that loss of the...
3.
Raunig D, Pennello G, Delfino J, Buckler A, Hall T, Guimaraes A, et al.
Acad Radiol
. 2022 Dec;
30(2):159-182.
PMID: 36464548
Multiparametric quantitative imaging biomarkers (QIBs) offer distinct advantages over single, univariate descriptors because they provide a more complete measure of complex, multidimensional biological systems. In disease, where structural and functional...
4.
Wang X, Pennello G, deSouza N, Huang E, Buckler A, Barnhart H, et al.
Acad Radiol
. 2022 Nov;
30(2):215-229.
PMID: 36411153
This paper is the fifth in a five-part series on statistical methodology for performance assessment of multi-parametric quantitative imaging biomarkers (mpQIBs) for radiomic analysis. Radiomics is the process of extracting...
5.
DuRoss A, Phan J, Lazar A, Walker J, Guimaraes A, Baas C, et al.
Wiley Interdiscip Rev Nanomed Nanobiotechnol
. 2022 Oct;
15(3):e1867.
PMID: 36308008
Radioenhancing nanoparticles (NPs) are being evaluated in ongoing clinical trials for various cancers including head and neck, lung, esophagus, pancreas, prostate, and soft tissue sarcoma. Supported by decades of preclinical...
6.
Huang E, Pennello G, deSouza N, Wang X, Buckler A, Kinahan P, et al.
Acad Radiol
. 2022 Oct;
30(2):196-214.
PMID: 36273996
Combinations of multiple quantitative imaging biomarkers (QIBs) are often able to predict the likelihood of an event of interest such as death or disease recurrence more effectively than single imaging...
7.
Chu L, Wang Z, Kambadakone A, Hecht E, He J, Narang A, et al.
Abdom Radiol (NY)
. 2022 Oct;
48(1):318-339.
PMID: 36241752
Purpose: Surgical resection is the only potential curative treatment for patients with pancreatic ductal adenocarcinoma (PDAC), but unfortunately most patients recur within 5 years of surgery. This article aims to...
8.
Delfino J, Pennello G, Barnhart H, Buckler A, Wang X, Huang E, et al.
Acad Radiol
. 2022 Oct;
30(2):183-195.
PMID: 36202670
This manuscript is the third in a five-part series related to statistical assessment methodology for technical performance of multi-parametric quantitative imaging biomarkers (mp-QIBs). We outline approaches and statistical methodologies for...
9.
Wyatt C, Guimaraes A
Magn Reson Med
. 2022 Mar;
88(1):151-163.
PMID: 35324040
Purpose: Seiffert spirals were recently explored as an efficient way to traverse 3D k-space compared to traditional 3D techniques. Several studies have shown the ability of 3D MR fingerprinting (MRF)...
10.
Johnson B, Creason A, Stommel J, Keck J, Parmar S, Betts C, et al.
Cell Rep Med
. 2022 Mar;
3(2):100525.
PMID: 35243422
Mechanisms of therapeutic resistance and vulnerability evolve in metastatic cancers as tumor cells and extrinsic microenvironmental influences change during treatment. To support the development of methods for identifying these mechanisms...