Alexander R Cools
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Explore the profile of Alexander R Cools including associated specialties, affiliations and a list of published articles.
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73
Citations
790
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Recent Articles
1.
Homberg J, Olivier J, VandenBroeke M, Youn J, Ellenbroek A, Karel P, et al.
Dis Model Mech
. 2016 Aug;
9(10):1147-1158.
PMID: 27483345
Social cognition is an endophenotype that is impaired in schizophrenia and several other (comorbid) psychiatric disorders. One of the modulators of social cognition is dopamine, but its role is not...
2.
Aono Y, Taguchi H, Saigusa T, Uchida T, Takada K, Takiguchi H, et al.
Behav Pharmacol
. 2014 Dec;
26(1-2):73-80.
PMID: 25438092
Intra-accumbal infusion of the α1-adrenergic agonist methoxamine, which has comparable affinity for α1A-, α1B- and α1D-adrenoceptor subtypes, fails to alter noradrenaline efflux but reduces dopamine efflux in the nucleus accumbens...
3.
Verheij M, Saigusa T, Koshikawa N, Cools A
Behav Pharmacol
. 2014 Oct;
26(1-2):81-90.
PMID: 25325287
It has previously been demonstrated that mesolimbic α-adrenoceptors, but not β-adrenoceptors, control the release of dopamine that is derived from reserpine-sensitive storage vesicles. The aim of the present study was...
4.
Meyer F, Latour J, Cools A, Verheij M
Front Cell Neurosci
. 2014 Oct;
8:243.
PMID: 25309315
Previous studies have shown that intra-accumbens infusion of isoproterenol (ISO), a beta-adrenoceptor-agonist, and phenylephrine (PE), an alpha-adrenoceptor-agonist, increase the release of accumbal dopamine (DA). In the present study we analyzed...
5.
Verheij M, Karel P, Cools A, Homberg J
Eur Neuropsychopharmacol
. 2014 Sep;
24(11):1850-4.
PMID: 25261262
It has recently been proposed that the increased reinforcing properties of cocaine and ecstasy observed in rats with a genetic deletion of serotonin transporters are the result of a reduction...
6.
van Vugt R, Meyer F, van Hulten J, Vernooij J, Cools A, Verheij M, et al.
Front Behav Neurosci
. 2014 Aug;
8:268.
PMID: 25157221
Schizophrenia is a complex mental disorder caused by an interplay between genetic and environmental factors, including early postnatal stressors. To explore this issue, we use two rat lines, apomorphine-susceptible (APO-SUS)...
7.
Aono Y, Saigusa T, Taguchi H, Uchida T, Takada K, Koshikawa N, et al.
Eur J Pharmacol
. 2013 May;
715(1-3):363-9.
PMID: 23665498
The effects of intra-accumbal infusion of selective agonists for the β-adrenoceptor subtypes on the noradrenaline and dopamine efflux in the nucleus accumbens of freely moving rats were investigated, using in...
8.
Verheij M, Saigusa T, Koshikawa N, Cools A
Neuropsychopharmacology
. 2013 Jan;
38(3):540-1.
PMID: 23322161
No abstract available.
9.
Ikeda H, Kamei J, Koshikawa N, Cools A
J Pharmacol Sci
. 2012 Oct;
120(3):152-64.
PMID: 23059952
Accumbal dopamine plays an important role in physiological responses and diseases such as schizophrenia, Parkinson's disease, and depression. Since the nucleus accumbens contains different neurotransmitters, it is important to know...
10.
Saigusa T, Aono Y, Uchida T, Takada K, Verheij M, Koshikawa N, et al.
Eur J Pharmacol
. 2012 May;
688(1-3):35-41.
PMID: 22617026
In vivo microdialysis was used to analyse the role of the α(1)- and α(2)-adrenoceptor subtypes in the regulation of noradrenaline and dopamine efflux in the nucleus accumbens of freely moving...