Alexander P Kao
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Explore the profile of Alexander P Kao including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
249
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Recent Articles
1.
Curto M, Dowsett J, Kao A, Tozzi G, Barber A
Sci Rep
. 2025 Feb;
15(1):6728.
PMID: 40000778
Structural materials are used extensively in nature where mechanical function is required. These structures are composites consisting of soft and, in some cases, hard phases precisely distributed over different length...
2.
Karali A, DallAra E, Zekonyte J, Kao A, Blunn G, Tozzi G
J Mech Behav Biomed Mater
. 2023 Jan;
138:105636.
PMID: 36608532
Exposure to X-ray radiation for an extended amount of time can cause damage to the bone tissue and therefore affect its mechanical properties. Specifically, high-resolution X-ray Computed Tomography (XCT), in...
3.
Rumney R, Rog J, Chira N, Kao A, Al-Khalidi R, Gorecki D
Front Pharmacol
. 2022 Aug;
13:935804.
PMID: 35910348
Ectopic calcification (EC) of myofibers is a pathological feature of muscle damage in Duchenne muscular dystrophy (DMD). Mineralisation of muscle tissue occurs concomitantly with macrophage infiltration, suggesting a link between...
4.
Rumney R, Robson S, Kao A, Barbu E, Bozycki L, Smith J, et al.
Nat Commun
. 2022 Jul;
13(1):3753.
PMID: 35798724
The biomaterial with the highest known tensile strength is a unique composite of chitin and goethite (α-FeO(OH)) present in teeth from the Common Limpet (Patella vulgata). A biomimetic based on...
5.
Cerrito P, Nava A, Radovcic D, Boric D, Cerrito L, Basdeo T, et al.
J R Soc Interface
. 2022 Feb;
19(187):20210820.
PMID: 35193386
The evolution of modern human reproductive scheduling is an aspect of our life history that remains vastly uncomprehended. The present work aims to address this gap by validating a non-destructive...
6.
Pena Fernandez M, Kao A, Bonithon R, Howells D, Bodey A, Wanelik K, et al.
Acta Biomater
. 2021 Jun;
131:424-439.
PMID: 34126266
Digital volume correlation (DVC) in combination with high-resolution micro-computed tomography (microCT) imaging and in situ mechanical testing is gaining popularity for quantifying 3D full-field strains in bone and biomaterials. However,...
7.
Macken W, Godwin A, Wheway G, Stals K, Nazlamova L, Ellard S, et al.
Genome Med
. 2021 Feb;
13(1):34.
PMID: 33632302
Background: Coat protein complex 1 (COPI) is integral in the sorting and retrograde trafficking of proteins and lipids from the Golgi apparatus to the endoplasmic reticulum (ER). In recent years,...
8.
Karali A, Kao A, Zekonyte J, Blunn G, Tozzi G
J Mech Behav Biomed Mater
. 2021 Jan;
115:104298.
PMID: 33445104
The overall mechanical behaviour of cortical bone is strongly dependant on its microstructure. X-ray computed tomography (XCT) has been widely used to identify the microstructural morphology of cortical tissue (i.e....
9.
Pena Fernandez M, Kao A, Witte F, Arora H, Tozzi G
J Biomech
. 2020 Nov;
113:110105.
PMID: 33181395
As a composite material, the mechanical properties of bone are highly dependent on its hierarchical organisation, thus, macroscopic mechanical properties are dictated by local phenomena, such as microdamage resulting from...
10.
Rumney R, Lanham S, Kanczler J, Kao A, Thiagarajan L, Dixon J, et al.
Sci Rep
. 2019 Nov;
9(1):17745.
PMID: 31780671
Deficient bone vasculature is a key component in pathological conditions ranging from developmental skeletal abnormalities to impaired bone repair. Vascularisation is dependent upon vascular endothelial growth factor (VEGF), which drives...