Alexander Merleev
Overview
Explore the profile of Alexander Merleev including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
684
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0
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Recent Articles
1.
Collins C, Khuat L, Sckisel G, Vick L, Minnar C, Dunai C, et al.
Front Immunol
. 2024 Sep;
15():1429912.
PMID: 39315105
The thymus is the central organ involved with T-cell development and the production of naïve T cells. During normal aging, the thymus undergoes marked involution, reducing naïve T-cell output and...
2.
Love N, Williams C, Killingbeck E, Merleev A, Doost M, Yu L, et al.
Sci Adv
. 2024 Jul;
10(28):eadm8206.
PMID: 38996022
Melanoma clinical outcomes emerge from incompletely understood genetic mechanisms operating within the tumor and its microenvironment. Here, we used single-cell RNA-based spatial molecular imaging (RNA-SMI) in patient-derived archival tumors to...
3.
Shimoda M, Inagaki T, Davis R, Merleev A, Tepper C, Maverakis E, et al.
PLoS Pathog
. 2023 Oct;
19(10):e1011703.
PMID: 37883374
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic double-stranded DNA virus and the etiologic agent of Kaposi's sarcoma and hyperinflammatory lymphoproliferative disorders. Understanding the mechanism by which KSHV increases the infected...
4.
Shimoda M, Inagaki T, Davis R, Merleev A, Tepper C, Maverakis E, et al.
bioRxiv
. 2023 Mar;
PMID: 36945595
Summary: KSHV causes multiple inflammatory diseases, however, the underlying mechanism is not clear. Shimoda et al. demonstrate that KSHV preferentially infects monocytes and utilizes virally encoded interleukin-6 to expand and...
5.
Ji-Xu A, Liakos W, Merleev A, Bruggen M, Nelson C
JAMA Dermatol
. 2023 Jan;
159(3):337-338.
PMID: 36652229
No abstract available.
6.
Merleev A, Ji-Xu A, Toussi A, Tsoi L, Le S, Luxardi G, et al.
JCI Insight
. 2022 Jul;
7(16).
PMID: 35862195
Proprotein convertase subtilisin/kexin type-9 (PCSK9) is a posttranslational regulator of the LDL receptor (LDLR). Recent studies have proposed a role for PCSK9 in regulating immune responses. Using RNA-Seq-based variant discovery,...
7.
Kumar A, Lyu Y, Yanagihashi Y, Chantarasrivong C, Majerciak V, Salemi M, et al.
Cell Rep
. 2022 May;
39(6):110788.
PMID: 35545047
Kaposi sarcoma-associated herpesvirus (KSHV) establishes a latent infection in the cell nucleus, but where KSHV episomal genomes are tethered and the mechanisms underlying KSHV lytic reactivation are unclear. Here, we...
8.
Lee L, Zhang H, Lee K, Liang H, Merleev A, Vincenti F, et al.
Front Immunol
. 2021 Jul;
12:679675.
PMID: 34220826
Alloreactive regulatory T cells (arTregs) are more potent than polyclonal Tregs at suppressing immune responses to transplant antigens. Human arTregs can be expanded with allogeneic CD40L-stimulated B cells (sBcs) or...
9.
Liakos W, Toussi A, Le S, Ma C, Merleev A, Marusina A, et al.
Dermatitis
. 2021 Jun;
32(6):e113-e115.
PMID: 34138776
No abstract available.
10.
Tuscano J, Poh C, Kaesberg P, Luxardi G, Merleev A, Marusina A, et al.
Clin Cancer Res
. 2021 Jun;
27(17):4726-4736.
PMID: 34088724
Purpose: Rituximab and lenalidomide are effective for previously untreated and relapsed/refractory (R/R) indolent non-Hodgkin lymphoma (iNHL). However, long-term survival and predictive biomarkers are not well described. Patients And Methods: We...