Alexander Manta
Overview
Explore the profile of Alexander Manta including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
225
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0
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Recent Articles
1.
Vanlieshout T, Stouth D, Raziee R, Sraka A, Masood H, Ng S, et al.
Med Sci Sports Exerc
. 2023 Oct;
56(3):486-498.
PMID: 37882083
Purpose: The purpose of this study was to determine how the intersection of coactivator-associated arginine methyltransferase 1 (CARM1) and biological sex affects skeletal muscle adaptations to chronic physical activity. Methods:...
2.
Ng S, Mikhail A, Mattina S, Manta A, Diffey I, Ljubicic V
FASEB J
. 2023 Apr;
37(5):e22863.
PMID: 37016990
Duchenne muscular dystrophy (DMD) is a life-limiting neuromuscular disorder characterized by muscle weakness and wasting. Previous proof-of-concept studies demonstrate that the dystrophic phenotype can be mitigated with the pharmacological stimulation...
3.
Mikhail A, Manta A, Ng S, Osborne A, Mattina S, Mackie M, et al.
Acta Physiol (Oxf)
. 2023 Feb;
237(4):e13943.
PMID: 36726043
Aim: Myotonic dystrophy type 1 (DM1) is the second most common muscular dystrophy after Duchenne and is the most prevalent muscular dystrophy in adults. DM1 patients that participate in aerobic...
4.
Mikhail A, Nagy P, Manta K, Rouse N, Manta A, Ng S, et al.
J Clin Invest
. 2022 Mar;
132(10).
PMID: 35316212
BackgroundMyotonic dystrophy type 1 (DM1) is a complex life-limiting neuromuscular disorder characterized by severe skeletal muscle atrophy, weakness, and cardiorespiratory defects. Exercised DM1 mice exhibit numerous physiological benefits that are...
5.
Stouth D, Vanlieshout T, Ng S, Webb E, Manta A, Moll Z, et al.
iScience
. 2020 Nov;
23(11):101755.
PMID: 33241200
Coactivator-associated arginine methyltransferase 1 (CARM1) is an emerging mediator of skeletal muscle plasticity. We employed genetic, physiologic, and pharmacologic approaches to determine whether CARM1 regulates the master neuromuscular phenotypic modifier...
6.
Manta A, OGrady J, Bleakney R, Theodoropoulos J
Can J Surg
. 2019 Jul;
62(4):224-226.
PMID: 31348627
In Ontario, Canada, wait times for magnetic resonance imaging (MRI) scans continue to exceed provincial targets. We sought to determine the incidence of inappropriate hip MRI scan referrals, based on...
7.
Manta A, Stouth D, Xhuti D, Chi L, Rebalka I, Kalmar J, et al.
J Physiol
. 2019 Jan;
597(5):1361-1381.
PMID: 30628727
Key Points: Myotonic dystrophy type 1 (DM1), the second most common muscular dystrophy and most prevalent adult form of muscular dystrophy, is characterized by muscle weakness, wasting and myotonia. A...
8.
Ng S, Manta A, Ljubicic V
Appl Physiol Nutr Metab
. 2018 Jun;
43(11):1194-1206.
PMID: 29944848
Neuromuscular disorders (NMDs) are chronic conditions that affect the neuromuscular system. Many NMDs currently have no cure; however, as more effective therapies become available for NMD patients, these individuals will...
9.
De Meulder B, Lefaudeux D, Bansal A, Mazein A, Chaiboonchoe A, Ahmed H, et al.
BMC Syst Biol
. 2018 May;
12(1):60.
PMID: 29843806
Background: Multilevel data integration is becoming a major area of research in systems biology. Within this area, multi-'omics datasets on complex diseases are becoming more readily available and there is...
10.
Dial A, Ng S, Manta A, Ljubicic V
Trends Endocrinol Metab
. 2018 Mar;
29(5):300-312.
PMID: 29572064
AMP-activated protein kinase (AMPK) is a primary regulator of cellular metabolism. Recent studies have revealed that AMPK also mediates the maintenance and plasticity of α-motoneurons, the neuromuscular junction, and skeletal...