Alexander L Richards
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Explore the profile of Alexander L Richards including associated specialties, affiliations and a list of published articles.
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3719
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Recent Articles
1.
Austin-Zimmerman I, Spinazzola E, Quattrone D, Wu-Choi B, Trotta G, Li Z, et al.
Psychol Med
. 2024 Dec;
:1-13.
PMID: 39637925
Background: The association between cannabis and psychosis is established, but the role of underlying genetics is unclear. We used data from the EU-GEI case-control study and UK Biobank to examine...
2.
van der Meer D, Cheng W, Rokicki J, Fernandez-Cabello S, Shadrin A, Smeland O, et al.
Schizophr Bull
. 2023 Oct;
50(2):327-338.
PMID: 37824720
Background: Schizophrenia is a highly heritable brain disorder with a typical symptom onset in early adulthood. The 2-hit hypothesis posits that schizophrenia results from differential early neurodevelopment, predisposing an individual,...
3.
Fusar-Poli L, Prachason T, Erzin G, Pries L, Brondino N, Politi P, et al.
Psychiatry Res
. 2023 Apr;
323:115184.
PMID: 37015164
Background: People with schizophrenia spectrum disorders (SSD) frequently present cognitive impairments. Here, we investigated whether the exposome score for schizophrenia (ES-SCZ) - a cumulative environmental exposure score - was associated...
4.
Richards A, Cardno A, Harold G, Craddock N, Di Florio A, Jones L, et al.
JAMA Psychiatry
. 2022 Aug;
79(10):1032-1039.
PMID: 36044200
Importance: Understanding the origins of clinical heterogeneity in bipolar disorder (BD) will inform new approaches to stratification and studies of underlying mechanisms. Objective: To identify components of genetic liability that...
5.
Trubetskoy V, Pardinas A, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli T, et al.
Nature
. 2022 Apr;
604(7906):502-508.
PMID: 35396580
Schizophrenia has a heritability of 60-80%, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and...
6.
Fusar-Poli L, Pries L, van Os J, Erzin G, Delespaul P, Kenis G, et al.
Prog Neuropsychopharmacol Biol Psychiatry
. 2021 Sep;
113:110440.
PMID: 34536513
Background: Social cognition impairments, such as facial emotion recognition (FER), have been acknowledged since the earliest description of schizophrenia. Here, we tested FER as an intermediate phenotype for psychosis using...
7.
Erzin G, Pries L, van Os J, Fusar-Poli L, Delespaul P, Kenis G, et al.
Eur Psychiatry
. 2021 Mar;
64(1):e25.
PMID: 33736735
Background: A cumulative environmental exposure score for schizophrenia (exposome score for schizophrenia [ES-SCZ]) may provide potential utility for risk stratification and outcome prediction. Here, we investigated whether ES-SCZ was associated...
8.
Hannon E, Dempster E, Mansell G, Burrage J, Bass N, Bohlken M, et al.
Elife
. 2021 Mar;
10.
PMID: 33646943
We performed a systematic analysis of blood DNA methylation profiles from 4483 participants from seven independent cohorts identifying differentially methylated positions (DMPs) associated with psychosis, schizophrenia, and treatment-resistant schizophrenia. Psychosis...
9.
van Os J, Pries L, Have M, de Graaf R, van Dorsselaer S, Delespaul P, et al.
Psychol Med
. 2020 Oct;
52(10):1910-1922.
PMID: 33070791
Background: There is evidence that environmental and genetic risk factors for schizophrenia spectrum disorders are transdiagnostic and mediated in part through a generic pathway of affective dysregulation. Methods: We analysed...
10.
Henquet C, van Os J, Pries L, Rauschenberg C, Delespaul P, Kenis G, et al.
Psychol Med
. 2020 Oct;
52(9):1777-1783.
PMID: 33046166
Background: This study attempted to replicate whether a bias in probabilistic reasoning, or 'jumping to conclusions'(JTC) bias is associated with being a sibling of a patient with schizophrenia spectrum disorder;...