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Alexander Klipp

Explore the profile of Alexander Klipp including associated specialties, affiliations and a list of published articles. Areas
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Citations 44
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Recent Articles
1.
Klipp A, Greitens C, Scherer D, Elsener A, Leroux J, Burger M
Adv Sci (Weinh) . 2025 Feb; :e2410815. PMID: 39998318
Gene delivery systems must overcome multiple barriers, with endosomal escape representing a prominent obstacle. This work has previously shown that a bacterial phospholipase C (PLC) enabled endosomal escape of a...
2.
Klipp A, Burger M, Leroux J
Adv Drug Deliv Rev . 2023 Aug; 200:115047. PMID: 37536508
RNA therapeutics offer great potential to transform the biomedical landscape, encompassing the treatment of hereditary conditions and the development of better vaccines. However, the delivery of RNAs into the cell...
3.
Deluigi M, Morstein L, Schuster M, Klenk C, Merklinger L, Cridge R, et al.
Nat Commun . 2022 Jan; 13(1):382. PMID: 35046410
α-adrenergic receptors (αARs) are G protein-coupled receptors that regulate vital functions of the cardiovascular and nervous systems. The therapeutic potential of αARs, however, is largely unexploited and hampered by the...
4.
Deluigi M, Klipp A, Klenk C, Merklinger L, Eberle S, Morstein L, et al.
Sci Adv . 2021 Feb; 7(5). PMID: 33571132
Neurotensin receptor 1 (NTSR1) and related G protein-coupled receptors of the ghrelin family are clinically unexploited, and several mechanistic aspects of their activation and inactivation have remained unclear. Enabled by...