Alexander Heine
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Explore the profile of Alexander Heine including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Heine A, Obst A, Opitz C, Halank M, Richter M, Lange T, et al.
Pneumologie
. 2024 Dec;
PMID: 39631731
A wide range of substances is currently available for the treatment of patients with pulmonary arterial hypertension. The current recommendations for initial drug therapy are based on the patient's risk...
2.
Kovacs G, Humbert M, Avian A, Lewis G, Ulrich S, Vonk Noordegraaf A, et al.
Eur Respir J
. 2024 Nov;
64(6).
PMID: 39603672
Background: Exercise pulmonary hypertension (PH) was defined by a mean pulmonary arterial pressure (mPAP)/cardiac output (CO) slope >3 mmHg·min·L between rest and exercise in the 2022 European Society of Cardiology/European...
3.
Geismann F, Braunschmidt L, Mohr A, Hardebusch T, Westhoff M, Dreher M, et al.
Pneumologie
. 2024 Aug;
79(1):80-86.
PMID: 39146969
Patients: Patients (n=751) with prolonged weaning (reason for ventilation "pneumonia" and "acute respiratory failure") from four centers for the period 2011-23 from the "WeanNet" registry were used as a matched...
4.
Schuler A, Yoon C, Caffarini E, Heine A, Meester A, Murray D, et al.
J Pharm Pract
. 2024 Jun;
38(1):155-167.
PMID: 38907529
The management of sedation in critically ill adults poses a unique challenge to clinicians. Dexmedetomidine, an α agonist, has a unique mechanism and favorable pharmacokinetics, making it an attractive intravenous...
5.
Habedank D, Ittermann T, Kaczmarek S, Stubbe B, Heine A, Obst A, et al.
Pulm Circ
. 2024 Jun;
14(2):e12398.
PMID: 38887743
Parameters of cardiopulmonary exercise testing significantly discriminate between healthy subjects and patients with pulmonary hypertension (PH), also according to the new 2022 definition of pulmonary hypertension (mean pulmonary arterial pressure...
6.
Ittermann T, Kaczmarek S, Obst A, Konemann R, Bahls M, Dorr M, et al.
Sci Rep
. 2024 Mar;
14(1):5394.
PMID: 38443426
Recently, the parameter internal work (IW) has been introduced as change in oxygen uptake (VO) between resting and unloading workload in cardiopulmonary exercise testing (CPET). The proportional IW (PIW) was...
7.
Abel P, Bulow R, Stubbe B, Heine A, Ewert R
Pneumologie
. 2023 Oct;
77(12):1009-1012.
PMID: 37857318
We report a case of a 43-year-old woman who suffered from recurrent pulmonary embolism leading to chronic thromboembolic pulmonary hypertension. Pulmonary endarterectomy was performed with good result. However, two years...
8.
Ralf E, Heine A, Obst A, Koerner K, Hustig-Kittler V, Boesche M, et al.
Sci Rep
. 2023 Apr;
13(1):6586.
PMID: 37085585
The establishment of a guideline for long-term noninvasive ventilation treatment (LTH-NIV) of acute hypercapnic exacerbations of chronic obstructive pulmonary disease (AECOPD) requiring acute ventilation has proven elusive. Most studies thus...
9.
Ewert R, Elhadad M, Habedank D, Heine A, Stubbe B
BMC Pulm Med
. 2023 Mar;
23(1):104.
PMID: 36991405
Background: Primary muscular disorders (metabolic myopathies, including mitochondrial disorders) are a rare cause of dyspnea. We report a case of dyspnea caused by a mitochondrial disorder with a pattern of...
10.
Ewert R, Ittermann T, Schmitt D, Pfeuffer-Jovic E, Stucke J, Tausche K, et al.
J Cardiovasc Dev Dis
. 2022 Oct;
9(10).
PMID: 36286285
Background: Following acute pulmonary embolism (PE), a relevant number of patients experience decreased exercise capacity which can be associated with disturbed pulmonary perfusion. Cardiopulmonary exercise testing (CPET) shows several patterns...