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Alexander Groisman

Explore the profile of Alexander Groisman including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 418
Followers 0
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Recent Articles
1.
Driscoll T, Bidone T, Ahn S, Yu A, Groisman A, Voth G, et al.
Biophys J . 2021 Sep; 120(20):4349-4359. PMID: 34509509
Conversion of integrins from low to high affinity states, termed activation, is important in biological processes, including immunity, hemostasis, angiogenesis, and embryonic development. Integrin activation is regulated by large-scale conformational...
2.
Lou S, Kennard A, Koslover E, Gutierrez E, Groisman A, Theriot J
Biophys J . 2021 Feb; 120(9):1578-1591. PMID: 33631203
During actin-based cell migration, the actin cytoskeleton in the lamellipodium both generates and responds to force, which has functional consequences for the ability of the cell to extend protrusions. However,...
3.
Allen G, Lee K, Barnhart E, Tsuchida M, Wilson C, Gutierrez E, et al.
Cell Syst . 2020 Sep; 11(3):286-299.e4. PMID: 32916096
Motile cells navigate complex environments by changing their direction of travel, generating left-right asymmetries in their mechanical subsystems to physically turn. Currently, little is known about how external directional cues...
4.
Zilony-Hanin N, Rosenberg M, Richman M, Yehuda R, Schori H, Motiei M, et al.
Small . 2019 Sep; 15(45):e1904203. PMID: 31482695
Nerve growth factor (NGF) plays a vital role in reducing the loss of cholinergic neurons in Alzheimer's disease (AD). However, its delivery to the brain remains a challenge. Herein, NGF...
5.
Zhang L, Bailey J, Subramanian R, Groisman A, Tezcan F
Nature . 2018 Jul; 560(7719):E31. PMID: 29973728
Change history: In this Letter, Alexander Groisman should have been listed as an author. This error has been corrected online.
6.
Zhang L, Bailey J, Subramanian R, Groisman A, Tezcan F
Nature . 2018 May; 557(7703):86-91. PMID: 29720635
The formation of condensed matter typically involves a trade-off between structural order and flexibility. As the extent and directionality of interactions between atomic or molecular components increase, materials generally become...
7.
Malinowski P, Cochet-Escartin O, Kaj K, Ronan E, Groisman A, Diamond P, et al.
Proc Natl Acad Sci U S A . 2017 Oct; 114(41):10888-10893. PMID: 28973880
Asexual freshwater planarians reproduce by tearing themselves into two pieces by a process called binary fission. The resulting head and tail pieces regenerate within about a week, forming two new...
8.
Kumar A, Ouyang M, van den Dries K, McGhee E, Tanaka K, Anderson M, et al.
J Cell Biol . 2016 Jul; 214(2):231. PMID: 27432899
No abstract available.
9.
Kumar A, Ouyang M, van den Dries K, McGhee E, Tanaka K, Anderson M, et al.
J Cell Biol . 2016 May; 213(3):371-83. PMID: 27161398
Integrin-dependent adhesions are mechanosensitive structures in which talin mediates a linkage to actin filaments either directly or indirectly by recruiting vinculin. Here, we report the development and validation of a...
10.
Deris J, Kim M, Zhang Z, Okano H, Hermsen R, Groisman A, et al.
Science . 2013 Nov; 342(6162):1237435. PMID: 24288338
To predict the emergence of antibiotic resistance, quantitative relations must be established between the fitness of drug-resistant organisms and the molecular mechanisms conferring resistance. These relations are often unknown and...