Alexander E Kabakov
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Explore the profile of Alexander E Kabakov including associated specialties, affiliations and a list of published articles.
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13
Citations
346
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Recent Articles
1.
Shestakova V, Smirnova E, Atiakshin D, Kisel A, Koryakin S, Litun E, et al.
Int J Mol Sci
. 2025 Mar;
26(5).
PMID: 40076619
The current treatment of radiation-induced skin wounds utilizes mainly conventional therapies, including topical steroids, creams, ointments, and hydrogel dressings, which do not take into account the immunologic changes that occur...
2.
Klabukov I, Kabakov A, Yakimova A, Baranovskii D, Sosin D, Atiakshin D, et al.
Curr Oncol
. 2025 Feb;
32(2).
PMID: 39996879
Chimeric antigen receptor (CAR)-T cell therapy yields good results in the treatment of various hematologic malignancies. However, the efficacy of CAR-T cell therapy against solid tumors has proven to be...
3.
Kabakov A, Gabai V
Cells
. 2021 Dec;
10(12).
PMID: 34943954
The high frequency of breast cancer worldwide and the high mortality among women with this malignancy are a serious challenge for modern medicine. A deeper understanding of the mechanisms of...
4.
Kabakov A, Yakimova A
Cancers (Basel)
. 2021 Apr;
13(5).
PMID: 33806538
Within aggressive malignancies, there usually are the "hypoxic zones"-poorly vascularized regions where tumor cells undergo oxygen deficiency through inadequate blood supply. Besides, hypoxia may arise in tumors as a result...
5.
Kabakov A, Gabai V
Methods Mol Biol
. 2017 Nov;
1709:107-127.
PMID: 29177655
Heat shock proteins are well-known protectors from cell death. Cell death (in particular, apoptosis and necrosis) is accompanied by certain hallmarks manifested as specific alterations in cellular membranes, cytoplasm, nucleus,...
6.
Kudryavtsev V, Khokhlova A, Mosina V, Selivanova E, Kabakov A
PLoS One
. 2017 Mar;
12(3):e0173640.
PMID: 28291803
We studied a role of the inducible heat shock protein 70 (Hsp70) in cellular response to radiosensitizing treatments with inhibitors of the heat shock protein 90 (Hsp90) chaperone activity. Cell...
7.
Kabakov A, Kudryavtsev V, Gabai V
Methods Mol Biol
. 2011 Sep;
787:231-44.
PMID: 21898239
Cell death (in particular, apoptosis and necrosis) is accompanied by appearance of certain hallmarks that are manifested as specific alterations in cellular membranes, cytoplasm, nucleus and mitochondria. Some of those...
8.
Kabakov A, Kudryavtsev V, Gabai V
J Mol Med (Berl)
. 2009 Dec;
88(3):241-7.
PMID: 19946660
The 90-kD heat shock protein (Hsp90) is an abundant molecular chaperone catalyzing maturation and activation of client proteins. A number of the Hsp90 client proteins are components of cancer cell-associated...
9.
Kabakov A, Makarova Y, Malyutina Y
Int J Radiat Oncol Biol Phys
. 2008 Apr;
71(3):858-65.
PMID: 18410996
Purpose: In addition to invasive tumor cells, endothelial cells (ECs) of the tumor vasculature are an important target for anticancer radiotherapy. The purpose of the present work is to investigate...
10.
Bryantsev A, Kurchashova S, Golyshev S, Polyakov V, Wunderink H, Kanon B, et al.
Biochem J
. 2007 Jul;
407(3):407-17.
PMID: 17650072
In vitro, small Hsps (heat-shock proteins) have been shown to have chaperone function capable of keeping unfolded proteins in a form competent for Hsp70-dependent refolding. However, this has never been...