Alexander E Gorbalenya
Overview
Explore the profile of Alexander E Gorbalenya including associated specialties, affiliations and a list of published articles.
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102
Citations
9398
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Recent Articles
11.
Calisher C, Carroll D, Colwell R, Corley R, Daszak P, Drosten C, et al.
Lancet
. 2021 Jul;
398(10296):209-211.
PMID: 34237296
No abstract available.
12.
Konings F, Perkins M, Kuhn J, Pallen M, Alm E, Archer B, et al.
Nat Microbiol
. 2021 Jun;
6(7):821-823.
PMID: 34108654
No abstract available.
13.
Jungreis I, Nelson C, Ardern Z, Finkel Y, Krogan N, Sato K, et al.
Virology
. 2021 Mar;
558:145-151.
PMID: 33774510
At least six small alternative-frame open reading frames (ORFs) overlapping well-characterized SARS-CoV-2 genes have been hypothesized to encode accessory proteins. Researchers have used different names for the same ORF or...
14.
Gorbalenya A, Siddell S
PLoS Pathog
. 2021 Mar;
17(3):e1009318.
PMID: 33662033
Species taxa are the units of taxonomy most suited to measure virus diversity, and they account for more than 70% of all virus taxa. Yet, as evidenced by the content...
15.
Slanina H, Madhugiri R, Bylapudi G, Schultheiss K, Karl N, Gulyaeva A, et al.
Proc Natl Acad Sci U S A
. 2021 Jan;
118(6).
PMID: 33472860
RNA-dependent RNA polymerases (RdRps) of the (, , and 12 other families) are linked to an amino-terminal (N-terminal) domain, called NiRAN, in a nonstructural protein (nsp) that is released from...
16.
Gulyaeva A, Gorbalenya A
Biochem Biophys Res Commun
. 2021 Jan;
538:24-34.
PMID: 33413979
Two pandemics of respiratory distress diseases associated with zoonotic introductions of the species Severe acute respiratory syndrome-related coronavirus in the human population during 21st century raised unprecedented interest in coronavirus...
17.
Gorbalenya A, Snijder E
Perspect Drug Discov Des
. 2020 Apr;
6(1):64-86.
PMID: 32288276
Dozens of novel cysteine proteinases have been identified in positive single-stranded RNA viruses and, for the first time, in large double-stranded DNA viruses. The majority of these proteins are distantly...
18.
Zell R, Gorbalenya A, Knowles N, Simmonds P, Skern T
Infect Genet Evol
. 2020 Feb;
81:104242.
PMID: 32061897
No abstract available.
19.
Gulyaeva A, Sigorskih A, Ocheredko E, Samborskiy D, Gorbalenya A
Bioinformatics
. 2020 Feb;
36(9):2731-2739.
PMID: 32003788
Motivation: To facilitate accurate estimation of statistical significance of sequence similarity in profile-profile searches, queries should ideally correspond to protein domains. For multidomain proteins, using domains as queries depends on...
20.
Kanitz M, Blanck S, Heine A, Gulyaeva A, Gorbalenya A, Ziebuhr J, et al.
Virology
. 2019 May;
533:21-33.
PMID: 31078932
Cavally virus (CavV) is a mosquito-borne plus-strand RNA virus in the family Mesoniviridae (order Nidovirales). We present X-ray structures for the CavV 3C-like protease (3CL), as a free enzyme and...