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Alexander Dubrovsky

Explore the profile of Alexander Dubrovsky including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 114
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Recent Articles
1.
Shirokov A, Navolokin N, Bucharskaya A, Blokhina I, Terskov A, Tzoy M, et al.
Discov Med . 2025 Feb; 37(193):335-347. PMID: 39973556
Background: Glioblastoma is an incurable and aggressive oncological disease of the brain. Recent studies have shown that transcranial non-invasive photobiomodulation is a promising new alternative method for suppression of glioblastoma...
2.
Shirokov A, Zlatogosrkaya D, Adushkina V, Vodovozova E, Kardashevskaya K, Sultanov R, et al.
Int J Mol Sci . 2024 Dec; 25(23). PMID: 39684263
Amyloid beta (Aβ) is a neuronal metabolic product that plays an important role in maintaining brain homeostasis. Normally, intensive brain Aβ formation is accompanied by its effective lymphatic removal. However,...
3.
Blokhina I, Terskov A, Evsiukova A, Dubrovsky A, Adushkina V, Zlatogorskaya D, et al.
Biomed Opt Express . 2024 Oct; 15(10):6063-6072. PMID: 39421760
Here, we present the new vascular effects of photodynamic therapy (PDT) with 5-aminolevulinic acid (5-ALA). PDT with 5-ALA induces a leakage of both the meningeal and cerebral blood vessels. The...
4.
Blokina I, Iluykov E, Myagkov D, Tuktarov D, Popov S, Inozemzev T, et al.
J Vis Exp . 2024 Jul; (208). PMID: 39007605
The meningeal lymphatic vessels (MLVs) play an important role in the removal of toxins from the brain. The development of innovative technologies for the stimulation of MLV functions is a...
5.
Shirokov A, Blokhina I, Fedosov I, Ilyukov E, Terskov A, Myagkov D, et al.
Biomedicines . 2024 Feb; 12(2). PMID: 38397864
There is an association between sleep quality and glioma-specific outcomes, including survival. The critical role of sleep in survival among subjects with glioma may be due to sleep-induced activation of...
6.
Semyachkina-Glushkovskaya O, Fedosov I, Zaikin A, Ageev V, Ilyukov E, Myagkov D, et al.
Biomed Opt Express . 2024 Jan; 15(1):44-58. PMID: 38223185
In this study on healthy male mice using confocal imaging of dye spreading in the brain and its further accumulation in the peripheral lymphatics, we demonstrate stronger effects of photobiomodulation...
7.
Semyachkina-Glushkovskaya O, Sergeev K, Semenova N, Slepnev A, Karavaev A, Hramkov A, et al.
Biomolecules . 2023 Nov; 13(11). PMID: 38002287
Anesthesia enables the painless performance of complex surgical procedures. However, the effects of anesthesia on the brain may not be limited only by its duration. Also, anesthetic agents may cause...
8.
Semyachkina-Glushkovskaya O, Bragin D, Fedosov I, Blokhina I, Khorovodov A, Terskov A, et al.
Adv Exp Med Biol . 2023 Oct; 1438:45-50. PMID: 37845438
There is strong evidence that augmentation of the brain's waste disposal system via stimulation of the meningeal lymphatics might be a promising therapeutic target for preventing neurological diseases. In our...
9.
Semyachkina-Glushkovskaya O, Bragin D, Bragina O, Socolovski S, Shirokov A, Fedosov I, et al.
Pharmaceutics . 2023 Feb; 15(2). PMID: 36839889
The progress in brain diseases treatment is limited by the blood-brain barrier (BBB), which prevents delivery of the vast majority of drugs from the blood into the brain. In this...
10.
Semyachkina-Glushkovskaya O, Shirokov A, Blokhina I, Telnova V, Vodovozova E, Alekseeva A, et al.
Pharmaceutics . 2023 Jan; 15(1). PMID: 36678667
The blood-brain barrier (BBB) limits the delivery of majority of cancer drugs and thereby complicates brain tumor treatment. The nasal-brain-lymphatic system is discussed as a pathway for brain drug delivery...