Alexander D Klose
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Explore the profile of Alexander D Klose including associated specialties, affiliations and a list of published articles.
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21
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Recent Articles
11.
Klose A
J Quant Spectrosc Radiat Transf
. 2010 Jul;
111(11):1852-1853.
PMID: 20607145
This note serves as an introduction to two papers by Klose et al. [Optical tomography using the time-independent equation of radiative transfer, Parts 1 (JQSRT 2002;72:691-713) and 2 (JQSRT 2002;72:715-732)]...
12.
Na I, Markley J, Tsai J, Yim N, Beattie B, Klose A, et al.
Blood
. 2010 Jun;
116(11):e18-25.
PMID: 20511541
We have developed a dual bioluminescent reporter system allowing noninvasive, concomitant imaging of T-cell trafficking, expansion, and activation of nuclear factor of activated T cells (NFAT) in vivo. NFAT activation...
13.
Klose A, Beattie B, Dehghani H, Vider L, Le C, Ponomarev V, et al.
Med Phys
. 2010 Feb;
37(1):329-38.
PMID: 20175496
Purpose: Bioluminescence imaging is a research tool for studying gene expression levels in small animal models of human disease. Bioluminescence light, however, is strongly scattered in biological tissue and no...
14.
Klose A
Opt Lett
. 2009 Aug;
34(16):2477-9.
PMID: 19684821
The proposed method exploits the spectral properties of tissue hemoglobin for the purpose of 3D image reconstruction of quantum dot reporter probes inside scattering tissue. It advances fluorescence tomography in...
15.
Beattie B, Klose A, Le C, Longo V, Dobrenkov K, Vider J, et al.
J Biomed Opt
. 2009 May;
14(2):024045.
PMID: 19405773
The procedures we propose make possible the mapping of two-dimensional (2-D) bioluminescence image (BLI) data onto a skin surface derived from a three-dimensional (3-D) anatomical modality [magnetic resonance (MR) or...
16.
Chu M, Vishwanath K, Klose A, Dehghani H
Phys Med Biol
. 2009 Apr;
54(8):2493-509.
PMID: 19336841
The accuracy of the commonly used diffusion approximation as used in diffuse optical tomography is known to be limited in cases involving strong absorption and in these situations a higher...
17.
Klose C, Klose A, Netz U, Beuthan J, Hielscher A
J Biomed Opt
. 2008 Nov;
13(5):050503.
PMID: 19021375
This research study explores the combined use of more than one parameter derived from optical tomographic images to increase diagnostic accuracy which is measured in terms of sensitivity and specificity....
18.
Song R, Klose A, Scheel A, Netz U, Beuthan J, Hielscher A
Conf Proc IEEE Eng Med Biol Soc
. 2007 Dec;
Suppl:6553-6.
PMID: 17959451
We have developed an images reconstruction algorithm to recover spatial distribution of optical properties in human finger joints for early diagnosis and monitoring of rheumatoid arthritis (RA). An optimization method...
19.
Klose A
J Opt Soc Am A Opt Image Sci Vis
. 2007 May;
24(6):1601-8.
PMID: 17491627
A stochastic image reconstruction methodology is proposed for solving the highly ill-posed inverse bioluminescent source problem in light-scattering media. The unknown source distribution is expressed in terms of a set...
20.
Hielscher A, Klose A, Scheel A, Moa-Anderson B, Backhaus M, Netz U, et al.
Phys Med Biol
. 2004 May;
49(7):1147-63.
PMID: 15128195
We present a novel optical tomographic imaging system that was designed to determine two-dimensional spatial distribution of optical properties in a sagittal plane through finger joints. The system incorporates a...