Alexander C Anderson
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Explore the profile of Alexander C Anderson including associated specialties, affiliations and a list of published articles.
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9
Citations
61
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Recent Articles
1.
Anderson A, Schultz B, Snow E, Brott A, Stangherlin S, Malloch T, et al.
bioRxiv
. 2024 Sep;
PMID: 39345430
Bacterial cell envelope polymers are commonly modified with acyl groups that provide fitness advantages. Many polymer acylation pathways involve pairs of membrane-bound -acyltransferase (MBOAT) and SGNH family proteins. As an...
2.
Colquhoun J, Farokhyfar M, Anderson A, Bethel C, Bonomo R, Clarke A, et al.
Microbiol Spectr
. 2023 Apr;
11(3):e0464622.
PMID: 37074187
The ADC (AmpC) β-lactamase is universally present in the Acinetobacter baumannii chromosome, suggesting it may have a yet-to-be-identified cellular function. Using peptidoglycan composition analysis, we show that overexpressing the ADC-7...
3.
Anderson A, Stangherlin S, Pimentel K, Weadge J, Clarke A
Glycobiology
. 2022 Jul;
32(10):826-848.
PMID: 35871440
The substitution and de-substitution of carbohydrate materials are important steps in the biosynthesis and/or breakdown of a wide variety of biologically important polymers. The SGNH hydrolase superfamily is a group...
4.
Anderson E, Shaji Saji N, Anderson A, Brewer D, Clarke A, Khursigara C
mSystems
. 2022 May;
7(3):e0015622.
PMID: 35545925
Epidemic strains of Pseudomonas aeruginosa are highly virulent opportunistic pathogens with increased transmissibility and enhanced antimicrobial resistance. Understanding the cellular mechanisms behind this heightened virulence and resistance is critical. Peptidoglycan...
5.
Anderson A, Burnett A, Constable S, Hiscock L, Maly K, Weadge J
Biochemistry
. 2021 Nov;
60(47):3659-3669.
PMID: 34762795
Biofilms are communities of self-enmeshed bacteria in a matrix of exopolysaccharides. The widely distributed human pathogen and commensal produces a biofilm matrix composed of phosphoethanolamine (pEtN)-modified cellulose and amyloid protein...
6.
Jones C, Anderson A, Clarke A
Proc Natl Acad Sci U S A
. 2021 Sep;
118(36).
PMID: 34480000
The O-acetylation of exopolysaccharides, including the essential bacterial cell wall polymer peptidoglycan, confers resistance to their lysis by exogenous hydrolases. Like the enzymes catalyzing the O-acetylation of exopolysaccharides in the...
7.
Seepersaud R, Anderson A, Bensing B, Choudhury B, Clarke A, Sullam P
J Biol Chem
. 2021 Jan;
296:100249.
PMID: 33384382
The serine-rich repeat (SRR) glycoproteins of gram-positive bacteria are a family of adhesins that bind to a wide range of host ligands, and expression of SRR glycoproteins is linked with...
8.
Scott W, Lowrance B, Anderson A, Weadge J
PLoS One
. 2020 Dec;
15(12):e0242686.
PMID: 33264329
Biofilms are community structures of bacteria enmeshed in a self-produced matrix of exopolysaccharides. The biofilm matrix serves numerous roles, including resilience and persistence, making biofilms a subject of research interest...
9.
Anderson A, Burnett A, Hiscock L, Maly K, Weadge J
J Biol Chem
. 2020 Mar;
295(18):6225-6235.
PMID: 32152228
Bacterial biofilms are cellular communities that produce an adherent matrix. Exopolysaccharides are key structural components of this matrix and are required for the assembly and architecture of biofilms produced by...