Alexander Brinkmann
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Explore the profile of Alexander Brinkmann including associated specialties, affiliations and a list of published articles.
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42
Citations
426
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Recent Articles
1.
Konig C, Frey O, Himmelein S, Mulack L, Brinkmann A, Perez Ruiz de Garibay A, et al.
Front Pharmacol
. 2024 Dec;
15:1447511.
PMID: 39737068
Background: Acute kidney injury (AKI) requiring continuous renal replacement therapy is common in critically ill patients. The ADVanced Organ Support (ADVOS) system is a novel hemodialysis machine that uses albumin...
2.
Morath B, Schultes L, Frey O, Rohr A, Christow H, Hoppe-Tichy T, et al.
Ther Drug Monit
. 2024 Sep;
PMID: 39289803
Background: Ampicillin/sulbactam, a combination of a β-lactam and β-lactamase inhibitor, is widely used in clinical settings. However, therapeutic drug monitoring (TDM) of ampicillin is not commonly performed, particularly in intensive...
3.
Schatz L, Greppmair S, Kunzelmann A, Starp J, Brinkmann A, Roehr A, et al.
Int J Antimicrob Agents
. 2024 Aug;
64(4):107305.
PMID: 39146997
Objectives: Piperacillin (PIP)/tazobactam is a frequently prescribed antibiotic; however, over- or underdosing may contribute to toxicity, therapeutic failure, and development of antimicrobial resistance. An external evaluation of 24 published PIP-models...
4.
Eckmann C, Aghdassi S, Brinkmann A, Pletz M, Rademacher J
Dtsch Arztebl Int
. 2024 Mar;
121(7):233-242.
PMID: 38440828
Background: Postoperative surgical site infections (SSI) account for almost 25% of all nosocomial infections in Germany and are a source of increased morbidity and mortality. Methods: This review is based...
5.
Chiriac U, Richter D, Frey O, Rohr A, Helbig S, Hagel S, et al.
Antibiotics (Basel)
. 2023 Jul;
12(7).
PMID: 37508207
Various studies have reported insufficient beta-lactam concentrations in critically ill patients. The optimal dosing strategy for beta-lactams in critically ill patients, particularly in septic patients, is an ongoing matter of...
6.
Greppmair S, Brinkmann A, Roehr A, Frey O, Hagel S, Dorn C, et al.
Intensive Care Med
. 2023 Jul;
49(8):966-976.
PMID: 37439872
Purpose: Inadequate piperacillin (PIP) exposure in intensive care unit (ICU) patients threatens therapeutic success. Model-informed precision dosing (MIPD) might be promising to individualize dosing; however, the transferability of published models...
7.
Kumpf O, Assenheimer M, Bloos F, Brauchle M, Braun J, Brinkmann A, et al.
Ger Med Sci
. 2023 Jul;
21:Doc10.
PMID: 37426886
The measurement of quality indicators supports quality improvement initiatives. The German Interdisciplinary Society of Intensive Care Medicine (DIVI) has published quality indicators for intensive care medicine for the fourth time...
8.
Schatz L, Brinkmann A, Rohr A, Frey O, Greppmair S, Weinelt F, et al.
Antimicrob Agents Chemother
. 2023 May;
67(5):e0010423.
PMID: 37125925
The altered pharmacokinetics of renally cleared drugs such as meropenem in critically ill patients receiving continuous renal replacement therapy (CRRT) might impact target attainment. Model-informed precision dosing (MIPD) is applied...
9.
Brauchle M, Deffner T, Brinkmann A, Dehner S, Dubb R, Finkeldei S, et al.
Med Klin Intensivmed Notfmed
. 2023 Apr;
118(5):351-357.
PMID: 37076742
In this white paper, key recommendations for visitation by children in intensive care units (ICU; both pediatric and adult), intermediate care units and emergency departments (ED) are presented. In ICUs...
10.
Liebchen U, Briegel J, Brinkmann A, Frey O, Wicha S
Intensive Care Med
. 2023 Jan;
49(4):475-476.
PMID: 36719458
No abstract available.