Alexander Bartelt
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Explore the profile of Alexander Bartelt including associated specialties, affiliations and a list of published articles.
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64
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3094
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Recent Articles
1.
El Bounkari O, Zan C, Yang B, Ebert S, Wagner J, Bugar E, et al.
Nat Commun
. 2025 Mar;
16(1):2297.
PMID: 40055309
Atherosclerosis is the underlying cause of myocardial infarction and ischemic stroke. It is a lipid-triggered and cytokine/chemokine-driven arterial inflammatory condition. We identify D-dopachrome tautomerase/macrophage migration-inhibitory factor-2 (MIF-2), a paralog of...
2.
Matta L, Weber P, Erener S, Walth-Hummel A, Hass D, Buhler L, et al.
Cell Rep
. 2025 Jan;
44(2):115225.
PMID: 39827461
Intermittent fasting (IF) is a nutritional lifestyle intervention with broad metabolic benefits, but whether the impact of IF depends on the individual's age is unclear. Here, we investigated the effects...
3.
Caca J, Bartelt A, Egea V
Int J Mol Sci
. 2025 Jan;
26(1.
PMID: 39795975
MicroRNAs (miRNAs) are short sequences of single-stranded non-coding RNAs that target messenger RNAs, leading to their repression or decay. Interestingly, miRNAs play a role in the cellular response to low...
4.
Ofoghi A, Kotschi S, Lemmer I, Haas D, Willemsen N, Bayer B, et al.
Cell Death Differ
. 2024 Oct;
32(3):480-487.
PMID: 39384955
Ferroptosis is an iron-dependent, non-apoptotic form of cell death initiated by oxidative stress and lipid peroxidation. Recent evidence has linked ferroptosis to the action of the transcription factor Nuclear factor...
5.
Brunetta H, Jung A, Valdivieso-Rivera F, de Campos Zani S, Guerra J, Furino V, et al.
EMBO J
. 2024 Sep;
43(21):4870-4891.
PMID: 39284909
While mechanisms controlling uncoupling protein-1 (UCP1) in thermogenic adipocytes play a pivotal role in non-shivering thermogenesis, it remains unclear whether FFo-ATP synthase function is also regulated in brown adipose tissue...
6.
Egea V, Lutterberg K, Steinritz D, Rothmiller S, Steinestel K, Caca J, et al.
Cell Death Dis
. 2024 Aug;
15(8):585.
PMID: 39127703
Sulfur mustard (SM) is a highly toxic chemical warfare agent. Exposure to SM results in various pathologies including skin lesions with subsequent impaired wound healing. To date, there are no...
7.
Berndt C, Alborzinia H, Amen V, Ayton S, Barayeu U, Bartelt A, et al.
Redox Biol
. 2024 Jun;
75:103211.
PMID: 38908072
Ferroptosis is a pervasive non-apoptotic form of cell death highly relevant in various degenerative diseases and malignancies. The hallmark of ferroptosis is uncontrolled and overwhelming peroxidation of polyunsaturated fatty acids...
8.
Wang Y, Li G, Chen B, Shakir G, Volz M, van der Vorst E, et al.
Cardiovasc Res
. 2024 Jun;
120(12):1411-1426.
PMID: 38838211
Aims: Although the cannabinoid CB1 receptor has been implicated in atherosclerosis, its cell-specific effects in this disease are not well understood. To address this, we generated a transgenic mouse model...
9.
Khani S, Topel H, Kardinal R, Tavanez A, Josephrajan A, Larsen B, et al.
Nat Metab
. 2024 Apr;
6(6):1053-1075.
PMID: 38684889
Promoting brown adipose tissue (BAT) activity innovatively targets obesity and metabolic disease. While thermogenic activation of BAT is well understood, the rheostatic regulation of BAT to avoid excessive energy dissipation...
10.
Guerra J, Matta L, Bartelt A
Herz
. 2024 Feb;
49(2):118-123.
PMID: 38329532
Cardiovascular diseases (CVD) are closely linked to protein homeostasis (proteostasis) and its failure. Beside genetic mutations that impair cardiac protein quality control, obesity is a strong risk factor for heart...