Alex L Mitchell
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Explore the profile of Alex L Mitchell including associated specialties, affiliations and a list of published articles.
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15
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5898
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Recent Articles
1.
Lin Q, Xavier B, Alako B, Mitchell A, Rajakani S, Glupczynski Y, et al.
Commun Biol
. 2022 Nov;
5(1):1217.
PMID: 36400841
Understanding the myriad pathways by which antimicrobial-resistance genes (ARGs) spread across biomes is necessary to counteract the global menace of antimicrobial resistance. We screened 17939 assembled metagenomic samples covering 21...
2.
Saary P, Mitchell A, Finn R
Genome Biol
. 2020 Sep;
21(1):244.
PMID: 32912302
Microbial eukaryotes constitute a significant fraction of biodiversity and have recently gained more attention, but the recovery of high-quality metagenomic assembled eukaryotic genomes is limited by the current availability of...
3.
Arikan M, Mitchell A, Finn R, Gurel F
J Food Sci
. 2020 Jan;
85(2):455-464.
PMID: 31957879
Kombucha, a fermented tea generated from the co-culture of yeasts and bacteria, has gained worldwide popularity in recent years due to its potential benefits to human health. As a result,...
4.
Mitchell A, Almeida A, Beracochea M, Boland M, Burgin J, Cochrane G, et al.
Nucleic Acids Res
. 2019 Nov;
48(D1):D570-D578.
PMID: 31696235
MGnify (http://www.ebi.ac.uk/metagenomics) provides a free to use platform for the assembly, analysis and archiving of microbiome data derived from sequencing microbial populations that are present in particular environments. Over the...
5.
Borsetto C, Amos G, da Rocha U, Mitchell A, Finn R, Laidi R, et al.
Microbiome
. 2019 May;
7(1):78.
PMID: 31118083
Background: The emergence of antibiotic-resistant pathogens has created an urgent need for novel antimicrobial treatments. Advances in next-generation sequencing have opened new frontiers for discovery programmes for natural products allowing...
6.
Milanese A, Mende D, Paoli L, Salazar G, Ruscheweyh H, Cuenca M, et al.
Nat Commun
. 2019 Mar;
10(1):1014.
PMID: 30833550
Metagenomic sequencing has greatly improved our ability to profile the composition of environmental and host-associated microbial communities. However, the dependency of most methods on reference genomes, which are currently unavailable...
7.
Almeida A, Mitchell A, Boland M, Forster S, Gloor G, Tarkowska A, et al.
Nature
. 2019 Feb;
568(7753):499-504.
PMID: 30745586
The composition of the human gut microbiota is linked to health and disease, but knowledge of individual microbial species is needed to decipher their biological roles. Despite extensive culturing and...
8.
Forster S, Kumar N, Anonye B, Almeida A, Viciani E, Stares M, et al.
Nat Biotechnol
. 2019 Feb;
37(2):186-192.
PMID: 30718869
Understanding gut microbiome functions requires cultivated bacteria for experimental validation and reference bacterial genome sequences to interpret metagenome datasets and guide functional analyses. We present the Human Gastrointestinal Bacteria Culture...
9.
Mitchell A, Attwood T, Babbitt P, Blum M, Bork P, Bridge A, et al.
Nucleic Acids Res
. 2018 Nov;
47(D1):D351-D360.
PMID: 30398656
The InterPro database (http://www.ebi.ac.uk/interpro/) classifies protein sequences into families and predicts the presence of functionally important domains and sites. Here, we report recent developments with InterPro (version 70.0) and its...
10.
Almeida A, Mitchell A, Tarkowska A, Finn R
Gigascience
. 2018 May;
7(5).
PMID: 29762668
Background: Taxonomic profiling of ribosomal RNA (rRNA) sequences has been the accepted norm for inferring the composition of complex microbial ecosystems. Quantitative Insights Into Microbial Ecology (QIIME) and mothur have...