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Alex L Kolodkin

Explore the profile of Alex L Kolodkin including associated specialties, affiliations and a list of published articles. Areas
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Articles 88
Citations 5012
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Recent Articles
1.
Sudarsanam S, Guzman-Clavel L, Dar N, Ziak J, Shahid N, Jin X, et al.
bioRxiv . 2025 Feb; PMID: 39896513
Cortical connectivity is contingent on ordered emergence of neuron subtypes followed by the formation of subtype-specific axon projections. Intracortical circuits, including long-range callosal projections, are crucial for information processing, but...
2.
James R, Hamilton N, Huffman L, Brown M, Neckles V, Pasterkamp R, et al.
Development . 2024 Nov; 151(22). PMID: 39495936
To form functional circuits, neurons must settle in their appropriate cellular locations, and then project and elaborate neurites to contact their target synaptic neuropils. Laminar organization within the vertebrate retinal...
3.
Kiraly J, Harris S, Al-Khindi T, Dunn F, Kolodkin A
J Vis Exp . 2024 Apr; (206). PMID: 38682904
The study of behavioral responses to visual stimuli is a key component of understanding visual system function. One notable response is the optokinetic reflex (OKR), a highly conserved innate behavior...
4.
Ziak J, Dorskind J, Trigg B, Sudarsanam S, Jin X, Hand R, et al.
EMBO J . 2024 Feb; 43(7):1214-1243. PMID: 38388748
Regulation of directed axon guidance and branching during development is essential for the generation of neuronal networks. However, the molecular mechanisms that underlie interstitial (or collateral) axon branching in the...
5.
Hunyara J, Daly K, Torres K, Yurgel M, Komal R, Hattar S, et al.
PLoS Biol . 2023 Dec; 21(12):e3002412. PMID: 38048352
Visual system function depends upon the elaboration of precise connections between retinal ganglion cell (RGC) axons and their central targets in the brain. Though some progress has been made in...
6.
Johnson T, Baranov P, Di Polo A, Fortune B, Gokoffski K, Goldberg J, et al.
Ophthalmol Sci . 2023 Nov; 3(4):100390. PMID: 38025164
Purpose: The Retinal Ganglion Cell (RGC) Repopulation, Stem Cell Transplantation, and Optic Nerve Regeneration (RReSTORe) consortium was founded in 2021 to help address the numerous scientific and clinical obstacles that...
7.
James R, Hamilton N, Huffman L, Pasterkamp J, Goff L, Kolodkin A
bioRxiv . 2023 Nov; PMID: 38014224
To form functional circuits, neurons must settle in their appropriate cellular locations and then project and elaborate neurites to contact their target synaptic neuropils. Laminar organization within the vertebrate retinal...
8.
Ziak J, Dorskind J, Trigg B, Sudarsanam S, Hand R, Kolodkin A
bioRxiv . 2023 Oct; PMID: 37873083
Regulation of directed axon guidance and branching during development is essential for the generation of neuronal networks. However, the molecular mechanisms that underlie interstitial axon branching in the mammalian brain...
9.
Dorskind J, Sudarsanam S, Hand R, Ziak J, Amoah-Dankwah M, Guzman-Clavel L, et al.
J Neurosci . 2023 Oct; 43(46):7745-7765. PMID: 37798130
Proper cortical lamination is essential for cognition, learning, and memory. Within the somatosensory cortex, pyramidal excitatory neurons elaborate axon collateral branches in a laminar-specific manner that dictates synaptic partners and...
10.
Soucy J, Aguzzi E, Cho J, Gilhooley M, Keuthan C, Luo Z, et al.
Mol Neurodegener . 2023 Sep; 18(1):64. PMID: 37735444
Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in irreversible vision loss due to the mammalian central nervous system's limited regenerative capacity. RGC repopulation is a...