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Alex Best

Explore the profile of Alex Best including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 670
Followers 0
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Recent Articles
1.
Best A, Guth S, Boots M
J Evol Biol . 2025 Mar; PMID: 40078008
Given their ubiquity in nature and their importance to human and agricultural health it is important to gain a better understanding of the drivers of the evolution of infectious disease....
2.
Singh P, Best A
Proc Biol Sci . 2024 Feb; 291(2017):20232610. PMID: 38378150
Understanding the coevolutionary dynamics of hosts and their parasites remains a major focus of much theoretical literature. Despite empirical evidence supporting the presence of sterility-mortality tolerance trade-offs in hosts and...
3.
Oliver M, Best A
J Evol Biol . 2024 Feb; 37(3):302-313. PMID: 38300519
Trophically transmitted parasites often infect an intermediate prey host and manipulate their behaviour to make predation more likely, thus facilitating parasite transmission to the definitive host. However, it is unclear...
4.
Pidwill G, Pyrah J, Sutton J, Best A, Renshaw S, Foster S
Sci Rep . 2023 Jan; 13(1):1188. PMID: 36681703
Staphylococcus aureus is a human commensal and also an opportunist pathogen causing life threatening infections. During S. aureus disease, the abscesses that characterise infection can be clonal, whereby a large...
5.
Singh P, Best A
Bull Math Biol . 2023 Jan; 85(3):16. PMID: 36670241
While experimental studies have demonstrated within-population variation in host tolerance to parasitism, theoretical studies rarely predict for polymorphism to arise. However, most theoretical models do not consider the crucial distinction...
6.
Wren L, Best A
Bull Math Biol . 2021 Nov; 83(12):124. PMID: 34773169
Susceptible-Infected-Recovered (SIR) models have long formed the basis for exploring epidemiological dynamics in a range of contexts, including infectious disease spread in human populations. Classic SIR models take a mean-field...
7.
Singh P, Best A
J Evol Biol . 2021 Oct; 34(12):1932-1943. PMID: 34704334
Tolerance and resistance are two modes of defence mechanisms used by hosts when faced with parasites. Here, we assume tolerance reduces infection-induced mortality rate and resistance reduces the susceptibility of...
8.
Best A, Singh P, Ward C, Vitale C, Oliver M, Idris L, et al.
R Soc Open Sci . 2021 Jun; 8(6):210712. PMID: 34150319
A common non-pharmaceutical intervention (NPI) during the COVID-19 pandemic has been group size limits. Furthermore, educational settings of schools and universities have either fully closed or reduced their class sizes....
9.
Best A, Ashby B
Proc Natl Acad Sci U S A . 2021 Apr; 118(18). PMID: 33853857
No abstract available.
10.
Ashby B, Best A
Curr Biol . 2021 Feb; 31(4):R174-R177. PMID: 33621500
Herd immunity is an important yet often misunderstood concept in epidemiology. As immunity accumulates in a population - naturally during the course of an epidemic or through vaccination - the...