Aleth Gaillard
Overview
Explore the profile of Aleth Gaillard including associated specialties, affiliations and a list of published articles.
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5
Citations
2535
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Recent Articles
1.
Tirosh I, Izar B, Prakadan S, Wadsworth 2nd M, Treacy D, Trombetta J, et al.
Science
. 2016 Apr;
352(6282):189-96.
PMID: 27124452
To explore the distinct genotypic and phenotypic states of melanoma tumors, we applied single-cell RNA sequencing (RNA-seq) to 4645 single cells isolated from 19 patients, profiling malignant, immune, stromal, and...
2.
Cunden L, Gaillard A, Nolan E
Chem Sci
. 2016 Feb;
7(2):1338-1348.
PMID: 26913170
Human S100A12 is a host-defense protein expressed and released by neutrophils that contributes to innate immunity. Apo S100A12 is a 21-kDa antiparallel homodimer that harbors two Ca(II)-binding EF-hand domains per...
3.
Wong A, Choi G, Cui C, Pregernig G, Milani P, Adam M, et al.
Proc Natl Acad Sci U S A
. 2016 Feb;
113(9):2544-9.
PMID: 26864203
The orchestrated action of genes controls complex biological phenotypes, yet the systematic discovery of gene and drug combinations that modulate these phenotypes in human cells is labor intensive and challenging...
4.
Di Francesco G, Gaillard A, Ghiviriga I, Abboud K, Murray L
Inorg Chem
. 2014 Apr;
53(9):4647-54.
PMID: 24745804
The synthesis and characterization of a family of tricopper clusters housed within a tris(β-diketimine) cyclophane ligand (H3L) that bear structural similarities to biological copper clusters are reported. In all complexes,...
5.
Brophy M, Nakashige T, Gaillard A, Nolan E
J Am Chem Soc
. 2013 Nov;
135(47):17804-17.
PMID: 24245608
Human calprotectin (CP) is an antimicrobial protein that coordinates Mn(II) with high affinity in a Ca(II)-dependent manner at an unusual histidine-rich site (site 2) formed at the S100A8/S100A9 dimer interface....