Alessia De Santis
Overview
Explore the profile of Alessia De Santis including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
5
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0
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Recent Articles
1.
De Santis A, Grifagni D, Orsetti A, Lenci E, Rosato A, DOnofrio M, et al.
Biomolecules
. 2024 Oct;
14(10).
PMID: 39456193
The conservation of the main protease in viral genomes, combined with the absence of a homologous protease in humans, makes this enzyme family an ideal target for developing broad-spectrum antiviral...
2.
Grifagni D, Lenci E, De Santis A, Orsetti A, Barracchia C, Tedesco F, et al.
ACS Med Chem Lett
. 2024 Feb;
15(2):250-257.
PMID: 38352832
We have applied a proteolysis targeting chimera (PROTAC) technology to obtain a peptidomimetic molecule able to trigger the degradation of SARS-CoV-2 3-chymotrypsin-like protease (3CL). The PROTAC molecule was designed by...
3.
Massai L, Grifagni D, De Santis A, Geri A, Cantini F, Calderone V, et al.
Biomolecules
. 2022 Nov;
12(11).
PMID: 36421689
Gold compounds have a long tradition in medicine and offer many opportunities for new therapeutic applications. Herein, we evaluated the lead compound Auranofin and five related gold(I) complexes as possible...